Cycloheximide (40 micrograms) intracerebroventricularly (i.c.v.) had no effect on thermoregulation against cold, but reduced fever due to an i.c.v. injection of leucocyte pyrogen (LP) by 25%, and reduced incorporation of radioactive leucine into hypothalamic protein by 94%.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2071853PMC
http://dx.doi.org/10.1111/j.1476-5381.1981.tb16763.xDOI Listing

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