Acute febrile neutrophilic dermatosis. Sweet's syndrome.

Acute febrile neutrophilic dermatosis (AFND) (Sweet's syndrome) is characterized by warm, erythematous plaques, accompanied by arthralgias, fever, and leukocytosis. A 53-year-old man was seen with chronic, recurrent, and unusually persistent AFND. The patient had a history of a gastrojejunostomy for peptic ulcer disease and had symptoms of the blind loop syndrome. Medical therapy for the blind loop syndrome failed to control his skin lesions, fever, or leukocytosis. His symptoms did respond to prednisone therapy, however. The relationship of AFND to the bowel bypass syndrome is discussed.