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Hemoglobin mass is accurately predicted in endurance athletes.
J Sports Sci
January 2025
Department of Nutrition Physiology, Institute of Sport-National Research Institute, Warsaw, Poland.
Hemoglobin mass (Hb) prediction enhance the accessibility and practicality of athletes' hemoglobin status monitoring, facilitating better performance. Therefore, we aimed to create prediction equations for Hb in well-trained endurance athletes (EA), based on easily obtained measures. The population of 220 well-trained EA (40% females, maximal oxygen uptake = 63.
View Article and Find Full Text PDFRisk prediction tools for pressure injury occurrence: an umbrella review of systematic reviews reporting model development and validation methods.
Diagn Progn Res
January 2025
Department of Applied Health Sciences, College of Medicine and Health, University of Birmingham, Edgbaston, Birmingham, UK.
Background: Pressure injuries (PIs) place a substantial burden on healthcare systems worldwide. Risk stratification of those who are at risk of developing PIs allows preventive interventions to be focused on patients who are at the highest risk. The considerable number of risk assessment scales and prediction models available underscores the need for a thorough evaluation of their development, validation, and clinical utility.
View Article and Find Full Text PDFBotulinum toxin type A for the treatment of patients with post-stroke spasticity in Thailand: cost-utility and budget impact analysis.
BMJ Open
January 2025
Siriraj Health Policy Unit, Mahidol University Faculty of Medicine Siriraj Hospital, Bangkok, Thailand
Objectives: To evaluate the cost-utility of botulinum toxin A (BoNT-A) for treating upper limb (UL) and lower limb (LL) post-stroke spasticity.
Design: Using a Markov model, adopting a societal perspective and a lifetime horizon with a 3% annual discount rate, the cost-utility analysis was conducted to compare BoNT-A combined with standard of care (SoC) with SoC alone. Costs, utilities, transitional probabilities and treatment efficacy were derived from 5-year retrospective data from tertiary hospitals and meta-analysis.
Near-Infrared Spectroscopy Allows for Monitoring of Bone Fracture Healing via Changes in Oxygenation.
J Funct Biomater
December 2024
Innovative Implant Development (Fracture Healing), Departments and Institutes of Surgery, Saarland University, 66421 Homburg, Germany.
Bone fractures are associated with hypoxia, but no longitudinal studies of perfusion measurements in human patients have been reported despite the clinical and research potential. In this longitudinal observational cohort study, the near-infrared spectroscopy (NIRS) device PortaMon was used to assess oxy-(OHb), deoxy-(HHb) and total (tHb) haemoglobin, as well as the differences between OHb and HHb (Hb) and the tissue saturation index (TSI) at three different depths in the fracture gap. Linear mixed effect models were fitted to analyse time effects.
View Article and Find Full Text PDFEffects of red blood cell transfusion on cerebral hemodynamics of preterm neonates.
Neurophotonics
October 2024
NICU Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Milan, Milan, Italy.
Significance: Anemia is a common problem in preterm neonates, and red blood cell transfusion (RBCT) is used to improve oxygen delivery. However, RBCT is associated with complications, although an increase in cerebral oxygenation has been documented, and no universally accepted biomarker for the need for transfusion (i.e.
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