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Absence of long-term incremental prognostic value of inducible wall motion abnormalities on dipyridamole stress CMR in patients with suspected or known coronary artery disease.
Eur Radiol
November 2024
Institute of Radiology, Department of Medicine, University of Padua, Padua, Italy.
Objectives: This single-center retrospective study evaluated the long-term (~5 years) prognostic value of dipyridamole stress cardiac magnetic resonance (CMR) in patients with known or suspected coronary artery disease (CAD), assessing the impact of both key phases of the ischemic cascade (perfusion and wall motion).
Material And Methods: We considered 322 consecutive patients who underwent dipyridamole stress CMR. Abnormal wall motion at rest and after dipyridamole, perfusion at stress and at rest, and late gadolinium enhancement (LGE) were analyzed.
Comparison of the Safety of Prednisone Plus Dipyridamole Versus Prednisone Plus Valsartan in the Treatment of Children with Primary Nephrotic Syndrome.
Iran J Kidney Dis
August 2024
Department of Pediatrics (No. 3 Ward), Northwest Women's and Children's Hospital, Xi'an, Shaanxi,710000, China.
Article Synopsis
- The study compares the effectiveness of two treatment combinations for pediatric nephrotic syndrome (NS): prednisone plus dipyridamole (Pred + DIP) and prednisone plus valsartan (Pred + VAL).
- Two hundred children with NS were divided into two groups, with results showing no significant differences in clinical efficacy or adverse reactions between treatments, but differences in coagulation and immune functions were noted.
- The findings suggest that while both treatments are effective, Pred + DIP enhances coagulation and immune functions, whereas Pred + VAL is better for reducing inflammation and managing blood lipid levels.
Transient ischaemic dilation ratio thresholds in patients with zero coronary calcium score undergoing exercise or dipyridamole stress SPECT myocardial perfusion imaging using a cadmium-zinc-telluride camera.
Eur Heart J Imaging Methods Pract
May 2023
Department of Cardiology, Tan Tock Seng Hospital, 11 Jln Tan Tock Seng, 308433 Singapore.
Aims: Transient ischaemic dilation (TID) is a marker of underlying extensive coronary artery disease (CAD) during myocardial perfusion imaging (MPI). The cut-off for a normal TID ratio (TIDr) value is often derived from a cohort of individuals with no apparent CAD. Varying criteria have been used to define the absence of CAD.
View Article and Find Full Text PDFPrognostic Value of Stress Perfusion Cardiac MRI in Cardiovascular Disease: A Systematic Review and Meta-Analysis of the Effects of the Scanner, Stress Agent, and Analysis Technique.
Radiol Cardiothorac Imaging
June 2024
From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China (Q.F.); Department of Radiology, Cambridge Biomedical Campus, University of Cambridge, Box 219, Level 5, Cambridge CB2 0QQ, England (Q.F., J.R.W.M.); Departments of Radiology (Q.F., J.R.W.M., S.A.) and Cardiology (S.P.H., G.A.), Royal Papworth Hospital, Cambridge, England; and School of Medicine & Population Health and INSIGNEO, Institute for In Silico Medicine, University of Sheffield, Sheffield, England (S.A.).
Purpose To perform a systematic review and meta-analysis to assess the prognostic value of stress perfusion cardiac MRI in predicting cardiovascular outcomes. Materials and Methods A systematic literature search from the inception of PubMed, Embase, Web of Science, and China National Knowledge Infrastructure until January 2023 was performed for articles that reported the prognosis of stress perfusion cardiac MRI in predicting cardiovascular outcomes. The quality of included studies was assessed using the Quality in Prognosis Studies tool.
View Article and Find Full Text PDFRestless Legs Syndrome (RLS) is a common sleep disorder characterized by an urge to move the legs that is responsive to movement (particularly during rest), periodic leg movements during sleep, and hyperarousal. Recent evidence suggests that the involvement of the adenosine system may establish a connection between dopamine and glutamate dysfunction in RLS. Transcranial magnetic stimulation (TMS) is a non-invasive electrophysiological technique widely applied to explore brain electrophysiology and neurochemistry under different experimental conditions.
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