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Assessment of Phrenic Nerve Pacers in a Patient With Congenital Central Hypoventilation Syndrome.
Pediatr Pulmonol
December 2024
Department of Pediatrics, New York Medical College, Valhalla, New York, USA.
The effects of low-dose morphine on sleep and breathlessness in COPD: A randomized trial.
Chest
December 2024
Flinders Health and Medical Research Institute/Adelaide Institute for Sleep Health, Flinders University, Adelaide, Australia.
Background: Low-dose morphine may be prescribed to reduce chronic breathlessness in chronic obstructive pulmonary disease (COPD). Recent subjective findings suggest morphine may influence breathlessness through sleep-related mechanisms. However, concerns exist regarding opioid safety in COPD.
View Article and Find Full Text PDFCentral sleep apnea as an initial presentation of small cell lung carcinoma with anti-Hu antibody-related paraneoplastic neurologic syndrome.
Respirol Case Rep
December 2024
Division of Critical Care Medicine, Department of Internal Medicine National Cheng Kung University Hospital Tainan Taiwan.
Anti-Hu antibody-related paraneoplastic neurologic syndrome (PNS), a rare disease primarily associated with small cell lung carcinoma, is characterized by diverse neurologic manifestations. Central sleep apnea, although rare, is specific to anti-Hu antibody-related PNS. Herein, we present a case of out-of-hospital cardiac arrest attributed to hypercapnic central sleep apnea and detail the subsequent workup that revealed anti-Hu brainstem encephalitis.
View Article and Find Full Text PDFThe Enigma That Is ROHHAD Syndrome: Challenges and Future Strategies.
Brain Sci
October 2024
Bristol Royal Hospital for Children, University Hospitals Bristol and Weston NHS Foundation Trust, Bristol BS2 8BJ, UK.
Rapid-onset obesity with hypoventilation, hypothalamic dysfunction, and autonomic dysregulation (ROHHAD) is a rare syndrome presenting in early childhood associated with a high risk of mortality between 50 and 60%. It is characterised by rapid, early onset of obesity between 1.5-7 years, along with central hypoventilation and hypothalamic dysfunction, such as central hypothyroidism, hyperprolactinemia, disorders of sodium and water balance, growth hormone deficiency, adrenocortical insufficiency, or disorders of puberty and features of autonomic dysregulation.
View Article and Find Full Text PDFInsights into the Overlap of Chronic Obstructive Pulmonary Disease and Sleep Apnea: Experience from the Clinic of Pneumology, Târgu Mureș.
Clin Pract
October 2024
Pulmonology Discipline, University of Medicine Pharmacy, Sciences and Technology "George Emil Palade", 540139 Târgu Mureș, Romania.
Introduction: Chronic obstructive pulmonary disease (COPD) has a severe impact on patients' health and can lead to multiple complications.
Material And Methods: We analyzed the co-occurrence of obstructive sleep apnea (OSA) in COPD patients hospitalized in the Pneumology Clinic of Târgu Mureș, Romania.
Results: A total of 150 COPD patients were investigated by clinical examination, STOP-BANG and Epworth questionnaires, ventilatory polygraphy (PG), EKG, cardiac ultrasound, blood lipids, and sugar.
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