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Tracing and strains causing septicemia in extremely preterm infants to the skin, mouth, and gut microbiota.
Appl Environ Microbiol
December 2024
Institute of Biomedicine, Department of Infectious Diseases,The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Unlabelled: Coagulase-negative staphylococci (CoNS) comprise about 50 species, some of which cause septicemia in preterm neonates. CoNS establish early on the skin and in the oral and gut microbiota, from where they may spread to the bloodstream. The colonization pattern preceding septicemia is not well-defined.
View Article and Find Full Text PDFGenus-targeted markers for the taxonomic identification and monitoring of coagulase-positive and coagulase-negative Staphylococcus species.
World J Microbiol Biotechnol
October 2024
Departamento de Biología, Facultad de Ciencias, Max Planck Tandem Group in Holobionts, Universidad Nacional de Colombia, Bogotá, Colombia.
The Staphylococcus genus comprises multiple pathogenic and opportunistic species that represent a risk to public health. Epidemiological studies require accurate taxonomic classification of isolates with enough resolution to distinguish clonal complexes. Unfortunately, 16 S rRNA molecular analysis and phenotypic characterization cannot distinguish all species and do not offer enough resolution to assess intraspecific diversity.
View Article and Find Full Text PDFBackground Coagulase-negative staphylococci (CoNS) are emerging as clinically significant pathogens. A high proportion of methicillin resistance along with intense biofilm-producing ability render CoNS-related infections challenging to treat. This study was undertaken to investigate the mechanisms of methicillin resistance, identify genes encoding for virulence, and their association with clinical outcomes among clinical isolates of Staphylococci in a tertiary care center.
View Article and Find Full Text PDFRapid Classification and Differentiation of Sepsis-Related Pathogens Using FT-IR Spectroscopy.
Microorganisms
July 2024
Centre for Metabolomics Research, Department of Biochemistry, Cell and Systems Biology, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool L69 7ZB, UK.
Sepsis is a life-threatening condition arising from a dysregulated host immune response to infection, leading to a substantial global health burden. The accurate identification of bacterial pathogens in sepsis is essential for guiding effective antimicrobial therapy and optimising patient outcomes. Traditional culture-based bacterial typing methods present inherent limitations, necessitating the exploration of alternative diagnostic approaches.
View Article and Find Full Text PDFMolecular characteristics and antibiotic resistance of Staphylococcus aureus and Staphylococcus haemolyticus isolated from bovine mastitis.
Res Vet Sci
September 2024
Institute of Animal Physiology, Centre of Biosciences of the Slovak Academy of Sciences, Šoltésovej 4/6, 040 01 Košice, Slovak Republic. Electronic address:
Staphylococci are classified as one of the pathogens causing bovine mastitis that can pose not only an economic loss to the dairy farms, but a serious public-health threat based on their zoonotic potential. We focused to monitor phenotypes of the isolated strains of Staphylococcus aureus (S. aureus) and Staphylococcus haemolyticus (S.
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