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Review of childhood genetic nephrolithiasis and nephrocalcinosis.
Front Genet
March 2024
Phoenix Children's Hospital, Department of Pediatrics, Division of Nephrology, Phoenix, AZ, United States.
Nephrolithiasis (NL) is a common condition worldwide. The incidence of NL and nephrocalcinosis (NC) has been increasing, along with their associated morbidity and economic burden. The etiology of NL and NC is multifactorial and includes both environmental components and genetic components, with multiple studies showing high heritability.
View Article and Find Full Text PDFReal-World Effectiveness of Preventive Pharmacological Therapy in Patients With Urolithiasis: A Retrospective Cohort Study.
Am J Kidney Dis
July 2024
Dow Division of Health Services Research, Department of Urology, Medical School, University of Michigan, Ann Arbor, Michigan; Division of Nephrology, Department of Internal Medicine, Medical School, University of Michigan, Ann Arbor, Michigan.
Rationale & Objective: Data supporting the efficacy of preventive pharmacological therapy (PPT) to reduce urolithiasis recurrence are based on clinical trials with composite outcomes that incorporate imaging findings and have uncertain clinical significance. This study evaluated whether the use of PPT leads to fewer symptomatic stone events.
Study Design: Retrospective cohort study.
Pharmacological Chemolysis of Uric Acid Lithiasis in A Patient with Crohn's Disease.
Arch Esp Urol
December 2023
Department of Urology, Consorcio Hospital General Universitario Valencia, 46014 València, Spain.
Patients with chronic diarrhoea or ileostomies suffer from electrolyte and urinary disorders and are prone to developing uric acid or calcium oxalate stones. Evidence is lacking regarding the management of uric acid stones in patients with inflammatory bowel diseases. We present the case of a male patient with Crohn's disease and carrying an ileostomy.
View Article and Find Full Text PDFRelationship between psoriasis and urolithiasis.
J Dermatol
February 2024
Department of Radiology, Giresun University School of Medicine, Giresun, Turkey.
The aim of the present study was to investigate whether patients with psoriasis are prone to urolithiasis. Prospective analysis of 67 patients diagnosed as psoriasis (PS group) and 65 volunteers who had never been diagnosed as psoriasis (NPS group) was performed. The levels of oxalate, citrate, calcium, uric acid, magnesium, creatinine, and sodium were evaluated by analyzing the 24-h urine samples.
View Article and Find Full Text PDFDrivers of calcium oxalate stone formation in the octogenarian population.
World J Urol
December 2023
Department of Urology, Icahn School of Medicine at Mount Sinai, New York, USA.
Introduction: American Urological Association (AUA) guidelines suggest metabolic testing via 24-h urine studies in high-risk, interested first-time stone formers, and recurrent stone formers. If metabolic testing is not available or otherwise not feasible, clinicians may need to utilize empiric therapy. Debility and social barriers, particularly in the elderly population, may limit the practicality of metabolic testing, and therefore, empiric therapy is of particular importance.
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