Ten dogs were used to compare conventional peripheral angiography and xeroradiographic angiography using three different concentrations of contrast material. Serial angiograms were produced in order to determine maximum arterial filling time, and a xeroradiograph was made at the predetermined maximal arterial phase. Xeroradiographic angiography consistently provided better imaging of the peripheral vessels and soft tissue. Reduction of the concentration of contrast material resulted in the loss of an image of diagnostic quality using conventional angiography, but vascular definition was maintained using xeroradiography. These studies indicate that xeroradiographic angiography not only improved peripheral vascular imaging, but is also successful at a lower concentration of contrast material, thus reducing toxic systemic effects and pain associated with the procedure.
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