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Am J Ophthalmol
January 2025
Professional Master Program in Artificial Intelligence in Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; Clinical Big Data Research Center, Taipei Medical University Hospital, Taipei Medical University, Taipei, Taiwan. Electronic address:
Purpose: This study assessed the performance of various deep learning models in predicting the postoperative outcomes of idiopathic epiretinal membrane (ERM) surgery based on preoperative optical coherence tomography (OCT) images.
Design: Validation of algorithms to predict the outcomes of ERM surgery based on OCT data.
Methods: Internal training and validation were performed using 1,392 OCT images from 696 eyes.
Acta Ortop Bras
January 2025
Hospital de Base do Distrito Federal, Departamento de Ortopedia e Traumatologia, Brasilia, DF, Brazil.
Objective: Evaluation of epidemiological data on Idiopathic Scoliosis in patients with different pectus subtypes.
Methods: A medical record analysis of 418 patients with pectus, associated with idiopathic scoliosis above 10°, with research on: subtypes of pectus (Lateral Pectus Carinatum, Inferior Pectus Carinatum, Superior Pectus Carinatum, Broad Pectus Excavatum, and Localized Pectus Excavatum), and characteristics of the scoliotic curve (Cobb angle, laterality, and location).
Results: The mean age was 14.
J Clin Med
January 2025
Department of Biomedical Engineering, University of Alberta, Edmonton, AB T6G 2G8, Canada.
: Idiopathic scoliosis (IS) is a common spinal deformity affecting 0.5% to 5.2% of children worldwide, with a higher reported range in Spain (0.
View Article and Find Full Text PDFInt J Mol Sci
January 2025
School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation, Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai 264005, China.
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and devastating lung disorder. In response to transforming growth factor-β (TGF-β), normal lung cells proliferate and differentiate into myofibroblasts, which are instrumental in promoting disease progression. Small interfering RNA (siRNA) targeting heat shock protein 47 (HSP47) has been demonstrated to alleviate IPF by blocking collagen synthesis and secretion.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Ophthalmology, Medical Research Institute, Pusan National University Hospital, Busan, South Korea.
Purpose: We investigated changes in macular topography and their association with visual acuity and metamorphopsia in the idiopathic epiretinal membrane (iERM).
Methods: Twenty-four eyes that underwent vitrectomy and ERM removal with internal limiting membrane peeling were included in this study. Best-corrected visual acuity (BCVA) and horizontal/vertical metamorphopsia scores (h and vM-scores in the M-chart) were assessed.
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