Kinetics of the process has been investigated employing differential spectroscopy technique. Possibility of synthesis of peptide bonds in aqueous solutions using aminoacyladenylates as condensing agents was shown. Analysis of the data obtained shows that the synthesis of peptide bond under the conditions investigated with the excess amounts of the second substrate follow the first order equation for irreversible reactions, the rate of the reaction decreasing with the increase in substrate concentrations. Velocity constants are determined for the first order reaction at different substrate concentrations. The data obtained are discussed in relation to the problem of abiogenic synthesis of biologically important macromolecules.
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