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Clinical characteristics and outcomes of chronic obstructive pulmonary disease patients with family history of chronic airway disease.
Ann Med
December 2025
Department of Pulmonary and Critical Care Medicine, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Background: Chronic Obstructive Pulmonary Disease (COPD) is a heterogeneous condition with different risk factors, including family history. This study aimed to explore association between a family history of chronic airway disease and features and outcomes of COPD.
Methods: Participants were obtained from the RealDTC study between December 2016 and December 2022.
Temporal Dynamics of Depressive Symptoms, Apathy, Daily Activities, and Cognitive Decline in Older People From the General Population: A Network Analysis.
Am J Geriatr Psychiatry
February 2025
Department of Psychiatry (AJCS, EJG), Leiden University Medical Center, Leiden, The Netherlands; Health Campus The Hague (EJG), Department of Public Health & Primary Care, Leiden University Medical Center, Leiden, The Netherlands. Electronic address:
Background: The prevalence of depressive symptoms, apathy, and cognitive decline increases with age. Understanding the temporal dynamics of these symptoms could provide valuable insights into the early stages of cognitive decline, allowing for more timely and effective treatment and management.
Methods: Participants from the Prevention of Dementia by Intensive Vascular Care (preDIVA) trial cohort with baseline and ≥3 follow-up measurements were included, with a median of 7.
The links between soil and water pollution and cardiovascular disease.
Atherosclerosis
March 2025
University Medical Center Mainz, Department of Cardiology at the Johannes Gutenberg University, Germany; German Cardiovascular Research Center (DZHK), Partner Site Rhine Main, Mainz, Germany.
Soil and water pollution represent significant threats to global health, ecosystems, and biodiversity. Healthy soils underpin terrestrial ecosystems, supporting food production, biodiversity, water retention, and carbon sequestration. However, soil degradation jeopardizes the health of 3.
View Article and Find Full Text PDFA comparison of the effectiveness of standard anterior bracket placement versus smile arc protection method: A randomized clinical trial.
J World Fed Orthod
March 2025
Dental Research Center, Orthodontics Department, Mashhad University of Medical Sciences, Mashhad, Iran. Electronic address:
Objectives: This randomized two-arm parallel trial aimed to compare the effectiveness of standard anterior bracket positioning with the smile arc protection (SAP) method in terms of occlusal and smile morphometric indices, and perceived post-treatment smile aesthetics.
Methods: Patients needing nonextraction orthodontic treatment were randomly assigned to either the SAP or standard bracket placement group. Inclusion criteria were ages 11 to 25 years, nonextraction treatment, and good oral hygiene, all treated using the Roth 0.
Sulfur traits in the plant microbiome: implications for sustainable agriculture.
Trends Microbiol
March 2025
Singapore Centre for Environmental Life Sciences Engineering, National University of Singapore, Singapore 117456, Singapore; Department of Biological Sciences, National University of Singapore, Singapore 117558, Singapore; NUS Environmental Research Institute, National University of Singapore, Singapore 117411, Singapore. Electronic address:
Owing to its biochemical flexibility, sulfur (S) is uniquely poised to fulfill versatile roles in plant-microbe interactions - impacting their metabolism with significant consequences for plant health and the global S cycle. We present evidence that the diversity of S-metabolic genes in plant-associated microbiomes (phytobiomes) is underappreciated, and plant niches are hotspots of bacterial S-metabolism with implications for S emissions. Building upon emerging findings, we posit that coordination of S-metabolism between plants and phytobiomes is a common mechanism for plant-microbe homeostasis and agriculturally beneficial microbial services.
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