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Biological, Biomechanical, and Histopathological Evaluation of Polyetherketoneketone Bioactive Composite as Implant Material.
J Biomed Mater Res B Appl Biomater
February 2025
Department of Prosthodontics, College of Dentistry, University of Baghdad, Baghdad, Iraq.
While polyetherketoneketone is a high-performance thermoplastic polymer, its hydrophobicity and inertness limit bone adhesion. This study aimed to evaluate a novel PEKK/CaSiO/TeO nanocomposite, comparing it to PEKK/15 wt.% CaSiO and PEKK groups.
View Article and Find Full Text PDFImpact of Collagenated and Non-Collagenated Deproteinized Bovine Bone Mineral on Schneiderian Membrane Integrity in Rabbits.
Dent J (Basel)
January 2025
Department of Oral Implantology, School of Dentistry, Osaka Dental University, 8-1 Kuzuhahanazonocho, Hirakata 573-1121, Osaka, Japan.
This investigation focused on the influence of collagen on the integrity of the Schneiderian membrane during maxillary sinus augmentation in a rabbit model. The aim of this study was to elucidate the relationship between membrane integrity and bone regeneration in augmented maxillary sinuses using collagenated and non-collagenated grafts, through detailed histological and histomorphometric analyses. In this forward-looking, randomized, split-mouth design, bilateral maxillary sinus augmentation was conducted on 12 rabbits.
View Article and Find Full Text PDFImpact of High Glucose on Bone Collagenous Matrix Composition, Structure, and Organization: An Integrative Analysis Using an Ex Vivo Model.
Cells
January 2025
Laboratory for Bone Metabolism and Regeneration, Faculty of Dental Medicine, University of Porto, 4200-393 Porto, Portugal.
Diabetes mellitus is a widespread metabolic disorder linked to numerous systemic complications, including adverse effects on skeletal health, such as increased bone fragility and fracture risk. Emerging evidence suggests that high glucose may disrupt the extracellular matrix (ECM) of bone, potentially altering its composition and organization. Collagen, the primary organic component of the ECM, is critical for maintaining structural integrity and biomechanical properties.
View Article and Find Full Text PDFHISTOMORPHOMETRIC AND IMMUNOHISTOCHEMICAL EVALUATION OF BONE HEALING AROUND IMPLANTS PLACED USING PIEZOSURGERY VS CONVENTIONAL DRILLS: A SPLITMOUTH PILOT STUDY.
J Oral Implantol
January 2025
Department of Neuroscience, Reproductive Sciences and Dentistry, Federico II University of Naples, Naples, Italy.
Purpose: This pilot study evaluated and compared histomorphometric and immunohistochemical characteristics of peri-implant bone tissue after implant site preparation using piezoelectric tips versus conventional drills.
Material And Methods: Six patients with bilateral partial edentulism underwent a splitmouth protocol. Twelve alveolar ridges were randomized into six control implant sites prepared using conventional drills (Drill Group); and six test implant sites prepared using piezoelectric implant inserts (Piezo Group).
The influence of different crosslinking agents onto the physical properties, integration behavior and immune response of collagen-based barrier membranes.
Front Bioeng Biotechnol
January 2025
Clinic and Policlinic for Dermatology and Venereology, University Medical Center Rostock, Rostock, Germany.
This study investigates the mechanical properties as well as and cyto- and biocompatibility of collagen membranes cross-linked with glutaraldehyde (GA), proanthocyanidins (PC), hexamethylendiisocyanate (HMDI) and 1-Ethyl-3-(3-dimethylaminopropyl) carbodiimide/N-hydroxysuccinimide (EC/NHS). A non-crosslinked membrane was used as reference control (RF). The initial cytotoxic analyses revealed that the PC, EC, and HMDI crosslinked membranes were cytocompatible, while the GA crosslinked membrane was cytotoxic and thus selected as positive control in the further study.
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