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Age- and Sex-Specific Regulation of Serine Racemase in the Retina of an Alzheimer's Disease Mouse.
Invest Ophthalmol Vis Sci
January 2025
State Key Laboratory of Ophthalmology, Optometry, and Visual Science, Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Purpose: Changes associated with Alzheimer's disease (AD) may have measurable effects on the retina, which may facilitate early detection due to the eye's accessibility. Retinal pathology and the regulation of serine racemase (SR) were investigated in the retinas of APP(SW)/PS1(∆E9) mice.
Methods: SR in the retinas and the content of D-serine in the aqueous humor were analyzed.
Thoracolumbar fascia ultrasound shear strain differs between low back pain and asymptomatic individuals: expanding the evidence.
Insights Imaging
January 2025
Department of Radiology, Radio-Oncology and Nuclear Medicine, Université de Montréal, Montreal, QC, Canada.
Objectives: To compare thoracolumbar fascia (TLF) shear strain between individuals with and without nonspecific low back pain (NSLBP), investigate its correlation with symptoms, and assess a standardized massage technique's impact on TLF shear strain.
Methods: Participants were prospectively enrolled between February 2021 and June 2022. Pre- and post-intervention TLF ultrasound and pain/disability questionnaires were conducted.
Background: Bariatric surgeries, such as laparoscopic sleeve gastrectomy (LSG), not only result in significant weight loss but also improve the inflammatory state in obese patients. This study aimed to investigate the effects of LSG on weight loss and inflammation status in bariatric patients 1-year post-procedure.
Methods: This prospective cohort study was conducted from September 2022 to May 2024.
Monitoring changes and multi-scenario simulations of land use and ecosystem service values in coastal cities: A case study of Qingdao, China.
Environ Monit Assess
January 2025
Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences, Beijing, 100101, China.
The study of land cover dynamics and the valuation of ecosystem services in coastal cities is pivotal for guiding sustainable urban development and conserving natural resources amidst the unique challenges posed by their geographical and ecological contexts. This study utilizes a 30 m × 30 m land use/cover change (LUCC) dataset to elucidate the spatiotemporal evolution of LUCC and ecosystem service value (ESV) and the trade-offs and synergistic relationships among ecosystem services in the coastal city of Qingdao under three different scenarios over the past 35 years and in the future based on the dual perspective of the past-future by using the equivalent factor approach (EFA), the PLUS model, and Spearman's rank correlation coefficient. The findings reveal a pronounced expansion in built-up areas in Qingdao from 1985 to 2020, with a concomitant significant reduction in cropland, leading to a fluctuation in the total ESV, which initially increased and then declined.
View Article and Find Full Text PDFTemporal lobe epilepsy with isolated amygdala enlargement: anatomo-electro-clinical features and long-term outcome.
J Neurol
January 2025
Epilepsy Unit - Sleep Disorders Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.
Background: Temporal lobe epilepsy with isolated amygdala enlargement (TLE-AE) still lacks a definite characterization and controversies exist.
Methods: We conducted a retrospective study identifying brain MRI scans with isolated AE between 2015 and 2021. We collected clinical and paraclinical data of patients with TLE-AE and evaluated the outcome.
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