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Enhanced Tolerance to Antifungals as a General Feature of Rho Mutants in Yeast Species: Implications to Positive Selection of Respiratory Deficiency.
Microorganisms
January 2025
Centre for Bioscience, Manchester Metropolitan University, John Dalton Building, Chester Street, Manchester M1 5GD, UK.
Although the mitochondrial genome is an attribute of all eukaryotes, some yeast species (called petite-positive) can replicate without mitochondrial DNA (mtDNA). Strains without mtDNA (known as rho mutants or petite mutants) are respiration-deficient and require fermentable carbon sources (such as glucose) for their metabolism. However, they are compromised in many aspects of fitness and competitiveness.
View Article and Find Full Text PDFAntifungal Effect of Cinnamon Bark Extract on the Phytopathogenic Fungus .
Food Technol Biotechnol
December 2024
University of Zagreb Faculty of Agriculture, Division of Phytomedicine, Department of Plant Pathology, Svetošimunska 25, 10000 Zagreb, Croatia.
Research Background: The use of plant extracts in the biological control of fungal plant diseases can reduce the use of fungicides and residues in food by effectively suppressing mycotoxigenic microorganisms. The focus of interest is therefore finding plant extracts that have antifungal properties and are not toxic to organisms, so that they can be used for the biological control of economically important phytopathogenic fungi such as . Species of the genus are considered economically important pathogenic fungi of numerous agricultural crops, which not only cause significant losses but also produce mycotoxins that reach consumers through food.
View Article and Find Full Text PDFAntifungal Potentials of Asian Plants: Ethnobotanical Insights and Phytochemical Investigations.
Chem Biodivers
January 2025
BRiCM: Bangladesh Reference Institute for Chemical Measurements, Natural Product Chemistry, Dhaka, 1205, Dhaka, BANGLADESH.
Introduction: Ethnomedicinal plants in Asia offer a promising, low-side-effect alternative to synthetic drugs for treating fungal infections, one of the most widespread communicable diseases caused by pathogenic fungi. Despite being underexplored, the region's rich plant diversity holds the potential for developing effective antifungal drugs. Research is increasingly focused on bioactive compounds from these plants, which show strong antifungal properties and may serve as leads for new drug development.
View Article and Find Full Text PDFUse of dielectric-barrier discharge (DBD) cold plasma for control of bread spoilage fungi.
Int J Food Microbiol
February 2025
Department of Food Engineering and Technology, School of Food Engineering, Universidade Estadual de Campinas, São Paulo, Brazil. Electronic address:
Bread is a greatly consumed bakery product worldwide. Unfortunately, it is an optimal substrate for fungal contamination and deterioration (aw > 0.95), commonly caused by the genera Penicillium, Paecilomyces, and Aspergillus, resulting in significant economic losses.
View Article and Find Full Text PDFAntifungal Properties of Polycephalomyces nipponicus (Ascomycetes) against Candida albicans: Potential for Novel Therapeutic Development.
Int J Med Mushrooms
December 2024
Department of Biology, Faculty of Science, Mahasarakham University, Kantarawichai District, Maha Sarakham, Thailand; Microbiology and Applied Microbiology Research Unit, Faculty of Science, Mahasarakham University, Kantarawichai District, Maha Sarakham, Thailand.
Candida albicans has the potential to turn pathogenic and cause mild to severe infections, particularly in people with weakened immune systems. Novel therapeutics are required due to its morphological alterations, biofilm development, and resistance to antifungal drugs. Polycephalomyces nipponicus, a traditional East Asian medicinal fungus, has shown potential as an antifungal agent.
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