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Article Synopsis
  • - A 75-year-old woman with abdominal pain and elevated inflammatory markers had a CT scan that revealed a perforated mass in her small intestine, leading to surgery and the discovery of a small intestinal leiomyosarcoma (LMS) after initial suspicion of a gastrointestinal stromal tumor (GIST).
  • - The diagnosis of LMS is challenging and can often be misclassified as GIST due to similar features; imaging studies like CT can help but are not always conclusive.
  • - This case emphasizes the importance of recognizing LMS as a potential cause of bowel perforation, highlighting the need for accurate diagnosis, multidisciplinary management, and long-term follow-up due to the high risk of recurrence and metastasis.
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Leiomyosarcoma of the small bowel presenting as an acute small bowel obstruction.

J Surg Case Rep

June 2024

Promedica Physicians General Surgery, Adrian Charles and Virginia Hickman Hospital, 5640 North Adrian Highway, Adrian, MI 49221 United States.

Leiomyosarcoma is a subtype of soft-tissue sarcoma, which is a rare soft-tissue malignancy comprising < 1% of adult cancers. There are a variety of etiologies of small bowel obstruction. Infrequently, small bowel malignancies can first present as small bowel obstruction.

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Leiomyosarcoma of the small bowel: A case report and literature review.

Int J Surg Case Rep

August 2022

Department of General Surgery, Hospital Mohamed Taher Maamouri, Nabeul, Tunisia; University Tunis El Manar, Faculty of Medicine of Tunis, Tunisia.

Introduction: Malignant tumors of the small bowel are rare. The jejunum, ileum, and duodenum represent the most common sites of intestinal leiomyosarcoma (LMS). Herein, we present a case of a 65-year-old patient having ileal LMS successfully treated with surgical resection.

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Leiomyosarcoma of the Mesentery.

Am Surg

September 2022

Department of Surgery, 6245Advent Health Hendersonville, Hendersonville, NC, USA.

The mesentery is a common site of metastasis from gastrointestinal, pancreatic, and biliary cancers. Primary mesenteric cancers are rare and usually mesenchymal and benign. Mesenteric leiomyosarcoma is a rare, malignant smooth muscle sarcoma with an incidence of 1:350000.

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