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Understanding Awareness, Utilization, and the Awareness-Utilization Gap of HIV PrEP and nPEP Among Young MSM in China.
AIDS Behav
January 2025
Vanke School of Public Health, Tsinghua University, Beijing, 100084, China.
HIV/AIDS remains a significant public health challenge in China, particularly among men who have sex with men (MSM). Pre-Exposure Prophylaxis (PrEP) and non-occupational post-exposure Prophylaxis (nPEP) are effective interventions to reduce HIV transmission in high-risk populations. This study assessed awareness and utilization levels of PrEP and nPEP among young MSM (YMSM) aged 18-29 in China and examined associated factors.
View Article and Find Full Text PDFA Small-Molecule Inhibitor of Gut Bacterial Urease Protects the Host from Liver Injury.
ACS Chem Biol
January 2025
Harvard University, Department of Chemistry and Chemical Biology, Cambridge, Massachusetts 02138, United States.
Hyperammonemia is characterized by the accumulation of ammonia within the bloodstream upon liver injury. Left untreated, hyperammonemia contributes to conditions such as hepatic encephalopathy that have high rates of patient morbidity and mortality. Previous studies have identified gut bacterial urease, an enzyme that converts urea into ammonia, as a major contributor to systemic ammonia levels.
View Article and Find Full Text PDFCONVENIENCE SAMPLING FOR PANDEMIC SURVEILLANCE OF SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 IN CHILDREN IN JACKSON, MISSISSIPPI.
Pediatr Infect Dis J
December 2024
Division of Infectious Diseases, Department of Pediatrics, University of Mississippi Medical Center.
We assessed severe acute respiratory syndrome coronavirus 2 seroprevalence on residual blood samples for pediatric COVID-19 surveillance: 2263 samples were collected during routine outpatient visits (<18 years, April 2020-August 2021). Seroprevalence increased over time, coinciding with or preceding virus circulation in the community and with or preceding pediatric severe COVID-19 hospitalization peaks. Residual blood sample seroprevalence may be a useful surveillance tool in future outbreaks.
View Article and Find Full Text PDFRacecadotril in the management of diarrhea: an underestimated therapeutic option?
Therap Adv Gastroenterol
January 2025
Operative Unit of Clinical Pharmacology and Pharmacovigilance, Renato Dulbecco University Hospital, Catanzaro, Italy.
Acute infectious diarrhea (AID) represents an important clinical entity both regarding morbidity and mortality rates, even in industrialized countries, and it leads to one of the major public health burdens, among gastroenterological diseases, with significant healthcare costs. Oral rehydration solution is the cornerstone of the therapy, but despite its proven efficacy in avoiding dehydration, it is still underused as it does not reduce the duration of diarrhea; hence, it is perceived as ineffective by caregivers. In this narrative review, we collected literature regarding the use of racecadotril, deeply discussing its role in the treatment of AID in both adults and children.
View Article and Find Full Text PDFImpact of digital device utilization on public health surveillance to enhance city resilience during the public health emergency response: A case study of SARS-CoV-2 response in Thailand (2020-2023).
Digit Health
January 2025
Department of Urban Development and Management, School of Public Affairs, Zhejiang University, Hangzhou, Zhejiang, China.
Objective: This study aims to examine the impact of digital devices on public health surveillance, the impact of public health surveillance on resilient cities, and the impact of digital devices on resilient cities.
Methods: Questionnaires were issued to residents of Thailand during the severe acute respiratory syndrome coronavirus 2 response (2020-2023). In total, 1025 valid responses were recorded from Thai nationals and expatriates.
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