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Unlabelled: Considering the similarity in clinical presentations of iris neoplasms of various origins, questions of their noninvasive diagnosis remain relevant. Optical coherence tomography angiography (OCT-A) is one of the imaging method that enables visualization of tumor vessels.
Purpose: This article examines the features of angioarchitecture, vascular network density, and perfusion density of iris melanoma and progressive iris nevus using OCT-A.
Iris changes and pupillometry in Nevus of Ota.
Clin Exp Optom
December 2024
Department of Ophthalmology, Guru Nanak Eye Centre, Maulana Azad Medical College, New Delhi, India.
Intraocular Pressure and Cup-to-Disc Ratio Asymmetry in Diagnosing Iris Melanoma.
Clin Ophthalmol
October 2024
Department of Ophthalmology, Stein Eye Institute, University of California Los Angeles, Los Angeles, CA, USA.
Article Synopsis
- The study aimed to differentiate iris melanoma from iris nevus by comparing intraocular pressure (IOP) and cup-to-disc ratio (CDR) in affected and unaffected eyes.
- Researchers analyzed data from 39 patients with iris melanoma and 40 with iris nevus, assessing IOP, CDR, and glaucoma diagnoses over nearly 10 years.
- Findings indicated that iris melanoma patients had significantly higher IOP and CDR in the affected eye compared to the unaffected eye, suggesting that IOP and CDR asymmetry could help in diagnosing iris melanoma.
Validation of a Dermatoscopy-Based Algorithm for the Diagnosis of Acral Melanoma.
Dermatology
December 2024
First Department of Dermatology, School of Medicine, Aristotle University, Thessaloniki, Greece.
Article Synopsis
- Diagnosing acral melanocytic lesions, like acral nevi and melanoma, can be difficult, and the BRAAFF checklist was developed to assist in this process but hasn't been validated yet.
- In a study, varying experts diagnosed images of nevi and melanomas using the BRAAFF checklist online, yielding a sensitivity of 92.5% and a specificity of 65.0%, comparable to traditional pattern recognition.
- The checklist showed varying levels of agreement among raters based on experience, and a simplified version achieved similar sensitivity with slightly lower specificity, suggesting that the BRAAFF checklist is a helpful but not superior diagnostic tool.
Clinical descriptive and long-term outcome of melanocytic uveal lesions in young dogs: 40 cases (45 eyes) including 13 cases of sector iridectomy.
Vet Ophthalmol
July 2024
Section of Ophthalmology, Department of Clinical Sciences and Advanced Medicine, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Purpose: To describe the clinical features surgical technique, early and long-term outcome with or without surgery, and histopathological findings of melanocytic anterior uveal lesions in young dogs.
Methods: Medical records of dogs at a guide dog facility removed from training due to a pigmented iris lesion were reviewed from 2014 to 2021. Selected dogs had surgical iridectomies performed.
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