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Measurement of Convexity Characteristics: A Transdisciplinary Consensus Conference.

J Wound Ostomy Continence Nurs

January 2025

Mikel Gray, PhD, RN, FNP, PNP, CUNP, CCCN, FAANP, WOCNF, FAAN, Department of Urology, University of Virginia, Charlottesville, Virginia.

While convex skin barriers have been used in patient care for decades, regulatory bodies and manufacturers have not established consistent parameters for measuring the most essential characteristics of a convex skin barrier. A transdisciplinary panel of manufacturers, engineers, marketing specialists and clinical subject matter experts from the United States was convened to address this gap. An initial consensus meeting was held to establish consensus around measurement parameters for 5 characteristics of convex skin barriers: depth, slope, flexibility, compressibility, and tension location.

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Conversion therapy is a treatment strategy that shifts from palliative systemic therapy to curative surgical treatment for primary and/or metastatic stage IV gastric cancer (GC). To address its clinical statements, the Korean Gastric Cancer Association aims to present a consensus on conversion therapy among experts attending KINGCA WEEK 2024. The KINGCA Scientific Committee and Development Working Group for Korean Practice Guidelines prepared preformulated topics and 9 clinical statements for conversion therapy.

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Expert Opinion on Multiple Myeloma Treatment in Brazil in the Bispecific Antibody Era.

Clin Lymphoma Myeloma Leuk

December 2024

Universidade Federal do Rio de Janeiro -UFRJ, Rio de Janeiro, Brazil; Instituto Americas de Ensino, Pesquisa e Inovação, Rio de Janeiro, Brazil.

Multiple myeloma treatment has evolved rapidly with the development of novel targeted therapies. The paper outlines multiple myeloma epidemiology, current treatments, and recent advances, highlighting the role of bispecific antibodies. Brazilian authorities have approved 3 bispecific antibodies (teclistamab, elranatamab, and talquetamab) for relapsed/refractory multiple myeloma patients who have received at least three prior therapies.

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Addressing Water Scarcity to Achieve Climate Resilience and Human Health.

Integr Environ Assess Manag

January 2025

Department of Medicine, Division of Occupational, Environmental and Climate Medicine, University of California, San Francisco; San Francisco, California, 94158United States.

Water scarcity is projected to affect half of the world's population, gradually exacerbated by climate change. This article elaborates from a panel discussion at the 2023 United Nations Water Conference on Addressing Water Scarcity to Achieve Climate Resilience and Human Health. Understanding and addressing water scarcity goes beyond hydrological water balances to also include societal and economic measures.

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: Monomicrobial necrotizing fasciitis is associated with exceedingly high mortality rates. Although effective antimicrobial therapy is an important part of treatment, the traditional microbiological diagnostic methods are not fast enough to meaningfully influence early therapeutic decisions. : Here, we report the application of the BioMérieux Biofire Filmarray Joint Infection Panel (BFJIP) for the rapid detection of the causative agent and susceptibility prediction in such a case.

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