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Combination of triple chemotherapy and sequential re-irradiation as salvage for recurrent treatment-refractory hemangiopericytoma of extraspinal dura: a case report.

Front Oncol

November 2024

Division of Abdominal Tumor Multimodality Treatment, Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

Introduction: Hemangiopericytoma (HPC) in the central nervous system (CNS) is rare. Our report aims to present an HPC case with multiple surgeries at the lumbar spine, and demonstrates an effective treatment as salvage.

Case Report: In this report, we present the case of a young girl with recurrent meningeal invasion of lumbar spinal HPC.

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Background: Hemangiopericytoma (HPC) is a rare secondary tumor after allogeneic hematopoietic stem cell transplantation (allo-HSCT), which has not been reported in the literature. Herein, we reported a case of HPC after allo-HSCT.

Case Description: We reported a case of a middle-aged female patient with primary plasma cell leukemia who presented lumbosacral pain and right lower limb pain and numbness on1684 days post-transplant.

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Spinal cord solitary fibrous tumors (SFTs), previously known as hemangiopericytoma (HPC), represent exceedingly rare neoplasms. Strategies for their management, such as appropriate follow-up duration, remain controversial due to their propensity for recurrence despite extended periods of quiescence. We report a 51-year-old male presenting with new-onset back pain and gait disturbances, who had undergone gross total resection (GTR) of an SFT within the thoracic spinal cord 19 years ago.

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Article Synopsis
  • Spinal hemangiopericytoma (sHPC) is a rare tumor that poses significant challenges due to its likelihood of recurrence and spread, making diagnosis and management difficult.
  • A 68-year-old female with multifocal sHPC underwent initial spinal surgery followed by years of stability, but later needed further treatments like radiosurgery after new growths were found through MRI.
  • The case highlights the need for ongoing monitoring and a collaborative treatment approach, with adaptable strategies to effectively manage the tumor and prioritize patient-centered care.
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Background And Objectives: The role of radiosurgery in the treatment of benign intracranial tumors is well established. However, there are limited long-term follow-up studies on outcomes after stereotactic radiosurgery (SRS) for benign intradural spinal tumors. In this article, we report a large single-institution experience in using SRS to treat patients with benign intradural tumors of the spine.

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