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Endoscopic management of transmural oesophageal defects following esophagectomy or spontaneous perforations, such as Boerhaave's syndrome, is often complicated by stent migration and luminal occlusion [1]. The Vacuum-Assisted Closure (VAC) stent, which integrates a covered stent with endoscopic vacuum therapy, aims to address these issues by providing functional drainage and promoting wound healing [2]. This case series presents our initial experience with VACStent therapy in four patients treated between February 2023 and April 2024.

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Boerhaave's syndrome is a rare critical condition manifesting as transmural esophageal rupture. It is usually associated with forceful emesis and increased intraesophageal pressure. Immediate aggressive surgical intervention is imperative in such cases.

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Spontaneous esophageal rupture, also known as Boerhaave syndrome, represents an unusual yet clinically significant condition characterized by the rupture of the esophageal wall due to a sudden increase in intraluminal pressure, typically induced by vomiting, concomitant with negative intrathoracic pressure dynamics. This condition poses a challenging clinical entity, presenting high mortality rates, especially when treatment is delayed. Surgical intervention is frequently employed as the primary management strategy, while non-surgical approaches, including stent placement and endoluminal vacuum therapy, are less commonly utilized.

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Article Synopsis
  • - Hamman's syndrome is a rare complication of diabetic ketoacidosis (DKA) that causes subcutaneous emphysema and spontaneous pneumomediastinum, as demonstrated in a case involving an 11-year-old boy with newly diagnosed type 1 diabetes.
  • - The patient showed classic DKA symptoms like excessive thirst, frequent urination, abdominal pain, and fatigue and was initially treated with IV fluids and insulin before being transferred to a specialized children's hospital.
  • - Upon examination, he showed signs of Hamman's syndrome, which was resolved with conservative treatment, emphasizing the need for awareness of this condition in pediatric DKA cases to ensure proper diagnosis and management.
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Introduction: Boerhaave syndrome is a rare condition associated with high morbidity and mortality. Prompt intervention greatly improves outcomes, with surgery traditionally being the mainstay of management. Recent advances in therapeutic endoscopy have led to increasing interest in endoluminal vacuum therapy (EVT), a minimally invasive technique, allowing wound debridement and drainage, encouraging granulation tissue formation.

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