The clinical, hematologic and biochemical study of three children, carriers of the double heterozygotous SN Baltimore hemoglobin from Guadeloupe, have not allowed to detect any typical anomaly and specially no sign of anemia or hemolysis. An iron deficiency of parasitologic origin has only been detected. This absence of pathological symptoms is related to the fact that SN red cells tend to sickle less rapidly than those from persons with sickle cell trait AS.

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