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MXene-based composite photocatalysts for efficient degradation of antibiotics in wastewater.
Sci Rep
December 2024
Department of Nano-Chemical Engineering, Faculty of Advanced Technologies, Shiraz University, Shiraz, Iran.
MXene-based (nano)materials have recently emerged as promising solutions for antibiotic photodegradation from aquatic environments, yet they are limited by scalability, stability, and selectivity challenges in practical settings. We formulated FeO-SiO/MXene ternary nano-photocomposites via coupled wet impregnation and sonochemistry approach for optimised tetracycline (TC) removal (the second most used antibiotic worldwide) from water using response surface methodology-central composite design (RSM-CCD). The photocatalysts containing various loading of FeO/SiO (5-45 wt%) on the MXene with a range of calcination temperatures (300-600 °C) via RSM optimisation were synthesised, characterised regarding crystallinity properties, surface morphology, binding energy, and light absorption capability, and analysed for TC degradation efficiency.
View Article and Find Full Text PDFResolvin D1 combined with exercise rehabilitation alleviates neurological injury in mice with intracranial hemorrhage via the BDNF/TrkB/PI3K/AKT pathway.
Sci Rep
December 2024
School of Basic Medicine, Dali University, Dali, 671003, Yunnan, China.
Resolvin D1 (RvD1) is an endogenous anti-inflammatory mediator that modulates the inflammatory response and promotes inflammation resolution. RvD1 has demonstrated neuroprotective effects in various central nervous system contexts; however, its role in the pathophysiological processes of intracerebral hemorrhage (ICH) and the potential protective mechanisms when combined with exercise rehabilitation remain unclear. A mouse model of ICH was established using collagenase, and treatment with RvD1 combined with three weeks of exercise rehabilitation significantly improved neurological deficits, muscle strength, learning, and memory in ICH mice while reducing anxiety-like behavior.
View Article and Find Full Text PDFFerredoxin 1 and 2 (FDX1/2) constitute an evolutionarily conserved FDX family of iron-sulfur cluster (ISC) containing proteins. FDX1/2 are cognate substrates of ferredoxin reductase (FDXR) and serve as conduits for electron transfer from NADPH to a set of proteins involved in biogenesis of steroids, hemes, ISC and lipoylated proteins. Recently, we showed that Fdx1 is essential for embryonic development and lipid homeostasis.
View Article and Find Full Text PDFSynthesis and molecular docking analysis of novel hydrazone and thiosemicarbazide derivatives incorporating a pyrimidine ring: exploring neuroprotective activity.
J Biomol Struct Dyn
December 2024
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Biruni University, Istanbul, Türkiye.
The increasing global prevalence of Alzheimer's disease necessitates the development of novel therapeutic approaches. Neurodegenerative diseases are associated with increased oxidative stress and levels of cholinesterase enzymes. Hence, the development of cholinesterase inhibitors and antioxidants may provide neuroprotective effects.
View Article and Find Full Text PDFH Consumption by Various Acetogenic Bacteria Follows First-Order Kinetics up to H Saturation.
Biotechnol Bioeng
December 2024
Department of Biological and Chemical Engineering, Aarhus University, Aarhus, Denmark.
Acetogenic bacteria play an important role in various biotechnological processes, because of their chemolithoautotrophic metabolism converting carbon dioxide with molecular hydrogen (H) as electron donor into acetate. As the main factor limiting acetogenesis is often H, insights into the H consumption kinetics of acetogens are required to assess their potential in biotechnological processes. In this study, initial H consumption rates at a range of different initial H concentrations were measured for three different acetogens.
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