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Validation and modification of existing bleeding complications prediction models for percutaneous renal biopsy: a prospective study.
PeerJ
December 2024
Department of Nephrology, Kidney Research Institute, West China Hospital of Sichuan University/West China School of Nursing, Sichuan University, Chengdu, China.
Background: Bleeding complications following percutaneous renal biopsy (PRB) are a significant clinical concern. This study aimed to validate and refine existing prediction models for post-biopsy bleeding to support more accurate clinical decision-making.
Methods: Clinical data from 471 PRB patients were examined in this prospective analysis.
[Prognosis and risk factors of IgA vasculitis nephritis in children].
Zhonghua Er Ke Za Zhi
December 2024
Department of Pediatric Nephrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan430030, China.
Article Synopsis
- The study focused on understanding the prognosis and risk factors for children with IgA vasculitis nephritis (IgAVN) by analyzing clinical data from 264 diagnosed patients over more than three years.
- Key findings revealed that the majority of patients presented with skin purpura and kidney issues such as hematuria and proteinuria, with most undergoing renal biopsies shortly after symptoms began.
- Statistical analyses were employed to assess factors influencing prognosis, and results indicated that younger children had higher rates of complete remission after three years compared to older age groups.
Effect of Ultrasound-Guided Renal Biopsies on Urinary N-Acetyl-Beta-D-Glucosaminidase Index Activity in Dogs with Diffuse Parenchymal Nephropathies.
Life (Basel)
July 2024
Department of Pathology, University of Agricultural Sciences and Veterinary Medicine, 400372 Cluj-Napoca, Romania.
Article Synopsis
- Ultrasound-guided kidney biopsy is a crucial diagnostic tool that helps differentiate between acute and chronic kidney diseases in dogs, aiding in accurate diagnosis and treatment decisions.
- A study involving 28 dogs revealed various nephropathy types, with glomerulonephritis being the most common, and highlighted significant effects like increased urinary iNAG levels post-biopsy, indicating kidney damage.
- All dogs experienced some degree of hematuria after the biopsy, which was transient and resolved without treatment, suggesting that while biopsy is invasive, side effects tend to be manageable.
Sonological predictors of complications of percutaneous renal biopsy-a prospective observational study.
Ir J Med Sci
October 2024
Department of Nephrology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.
Unlabelled: Percutaneous renal biopsy, although essential for renal disease diagnosis, is associated with a number of post-biopsy complications ranging from gross haematuria to AV fistula to death. In this study, we carried out an active haematoma surveillance and attempted to correlate renal sonological parameters-kidney length, renal parenchymal changes, renal cortical and parenchymal thickness for their potential use in prediction of post-renal biopsy complications.
Methods: This was a prospective study done from April 2022 to April 2023 on all adult patients undergoing native or transplant kidney biopsy.
Post-renal Biopsy Retroperitoneal Haematoma Accompanied by Decreased Coagulation Factor XIII Levels in Immunoglobulin A Nephropathy.
Cureus
February 2024
Department of Pediatrics, The University of Tokyo, Tokyo, JPN.
Article Synopsis
- Post-biopsy bleeding, particularly retroperitoneal haematoma, is a serious but rare complication primarily observed in patients with specific risk factors or vascular issues.
- A case study of a 14-year-old male with IgA nephropathy (IgAN) showed delayed bleeding due to a retroperitoneal haematoma following a renal biopsy, despite initially normal coagulation assessments.
- The case highlighted a mild deficiency in coagulation factor XIII (FXIII) discovered post-procedure, suggesting that undiagnosed bleeding disorders like FXIII deficiency could elevate the risk of bleeding complications after renal biopsies, underscoring the need for comprehensive evaluation prior to these procedures.
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