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Relationship between ZHX2 Expression and VHL Gene Alteration in VHL-associated and Sporadic Hemangioblastomas of the Central Nervous System.
J Kidney Cancer VHL
December 2024
Department of Urology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Central nervous system hemangioblastoma (CNS-HB) is the most common manifestation of von Hippel-Lindau disease (VHL). The main axis of the CNS-HB pathway is the VHL-HIF signaling pathway. Recently, we proposed an alternative VHL-JAK-STAT pathway in CNS-HB.
View Article and Find Full Text PDFElectrochemical insights into the direct dissolution of impure sphalerites and their partial oxidation in an acidic environment.
Sci Rep
January 2025
Department of Mining and Explosives Engineering, Missouri University of Science and Technology, Rolla, MO, 65409, USA.
This study examined the electrodissolution mechanism of five impure sphalerite samples, which differ significantly in purity levels, along with their partially oxidized counterparts in a 0.5 M HSO. Partially oxidized samples were prepared through an incomplete leaching of sphalerite using HSO with Fe(SO).
View Article and Find Full Text PDFWater-Deficient Interface Induced via Hydrated Eutectic Electrolyte with Restrictive Water to Achieve High-Performance Aqueous Zinc Metal Batteries.
Small
January 2025
State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, Wuhan, 430070, China.
The development of aqueous zinc metal batteries (AZMBs) is hampered by dendrites and side reactions induced by reactive HO. In this study, a hydrated eutectic electrolyte with restrictive water consisting of zinc trifluoromethanesulfonate (Zn(OTf)), 1,3-propanediol (PDO), and water is developed to improve the stability of the anode/electrolyte interface in AZMBs via the formation of a water-deficient interface. Additionally, PDO participates in the Zn solvation structure and inhibits the movement of water molecules.
View Article and Find Full Text PDFThe interplay between ZigA and SltB promotes zinc homeostasis and cell envelope integrity.
Infect Immun
January 2025
Department of Pathology Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
is an opportunistic human pathogen that acquires nutrient metals from the vertebrate host amid infection. During zinc (Zn) scarcity, upregulates the expression of the predicted Zn metallochaperone, . Loss of compromises fitness during Zn deficiency, highlighting its role in this condition.
View Article and Find Full Text PDFEffect of zinc level and the thermal environment on the zootechnical performance and tibia-breaking strength of Japanese quails.
Front Vet Sci
January 2025
Research Group in Bioclimatology, Ethology and Animal Welfare (BioEt), Department of Animal Science, Federal University of Paraiba, Areia, Paraiba, Brazil.
Japanese quails () are sensitive to zinc (Zn) deficiency, a mineral essential for growth, development, and bone health. This study evaluated the effects of different levels of Zn in the diet on zootechnical performance, organ and carcass weight, and tibial breakage resistance in quails from 1 to 42 days of age. A 5 × 2 factorial design was used, consisting of five Zn levels (30, 60, 90, 120, and 150 mg/kg) and two thermal environments (thermal comfort and heat stress), with five replicates of 10 birds per treatment.
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