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The Immunoexpression and Prognostic Significance of Stem Cell Markers in Malignant Salivary Gland Tumors: A Systematic Review and Meta-Analysis.
Genes (Basel)
December 2024
School of Dentistry, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Salivary gland carcinomas encompass a broad group of malignant lesions characterized by varied prognoses. Stem cells have been associated with the potential for self-renewal and differentiation to various subpopulations, resulting in histopathological variability and diverse biological behavior, features that characterize salivary gland carcinomas. This study aims to provide a thorough systematic review of immunohistochemical studies regarding the expression and prognostic significance of stem cell markers between different malignant salivary gland tumors (MSGTs).
View Article and Find Full Text PDFDermoscopy of Basal Cell Carcinoma Part 2: Dermoscopic Findings by Lesion Subtype, Location, Age of Onset, Size and Patient Phototype.
Cancers (Basel)
January 2025
Department of Dermatology, Institute of Medical Sciences, Medical College, Rzeszow University, 35-310 Rzeszow, Poland.
Basal cell carcinoma (BCC) is the most prevalent type of skin cancer worldwide. Despite its low metastatic potential, certain subtypes present an aggressive clinical course. Part II focuses on the different dermoscopic patterns observed in BCC, depending on the lesion subtype, its location on the body, the patient's age, the size of the tumor, and skin phototype.
View Article and Find Full Text PDFAtypical and worrisome histological features in pleomorphic adenoma: challenging and potentially significant diagnostic pitfall.
Virchows Arch
January 2025
Department of Pathology, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic.
Pleomorphic adenoma (PA), the most prevalent salivary gland tumor, exhibits a diverse histological spectrum characterized by epithelial, myoepithelial, and mesenchymal patterns, and secretory products. However, a subset of PAs presents microscopic features suggestive of malignancy, leading to challenging and potentially significant diagnostic pitfalls. A comprehensive retrospective analysis was conducted on the Salivary Gland Tumor Registry, compiled by the authors.
View Article and Find Full Text PDFTreatment-Resistant Chromoblastomycosis Successfully Managed With Surgical Excision.
Cureus
November 2024
Dermatology, University of California Davis Medical Center, Sacramento, USA.
Chromoblastomycosis is an uncommon, chronic granulomatous fungal infection of the skin and subcutaneous tissue. Chromoblastomycosis is most commonly caused by the traumatic inoculation of dematiaceous (pigmented) fungi, most commonly species, species, and species. Chromoblastomycosis usually affects agricultural workers in tropical and subtropical climates.
View Article and Find Full Text PDFLichenoid paraneoplastic pemphigus in a patient presenting with follicular lymphoma: a review of the literature.
Arch Dermatol Res
November 2024
Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, 1295 NW 14th St, Miami, FL, 33125, USA.
Article Synopsis
- Paraneoplastic pemphigus (PNP) is a rare autoimmune blistering disease linked to cancer, typically presenting with severe mouth sores and varied skin eruptions.
- The case study details a patient with follicular lymphoma (FL) who developed symptoms of PNP, prompting a review of current treatment options and understanding of the disease.
- Despite potential remission from related cancers, PNP has a low 5-year survival rate, highlighting the urgent need for more research and suggesting that T cell immunosuppressive therapy might help FL patients with PNP.
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