The effects of 0.8 g alcohol kg-1 on CNS processes as reflected in EEG changes were studied in controlled experiments in 14 subjects in relation to BAC levels. A Two Period Change-Over Design with repeated trials over time allowed us to ascertain the time course and to isolate alcohol-induced changes from diurnal variations and effects of sequence and period. Based on spectral analysis of analog EEG recordings, the study has shown differential patterns of bi-phasic or tri-phasic alcohol-induced EEG changes over time in a number of parameters in background and in stimulus-elicited EEG responses varying with the BAC level and the metabolic phase of alcohol biotransformation. An increase in alpha activity during the absorption phase, a shift in the median of the total spectral power to the right (upwards), a decrease in slow activity in the delta and theta bands, and a decrease in variability of the background EEG on one hand and a reduction in stimulus-elicited EEg responses in total spectral alpha, theta and delta bands on the other are all interpreted as a stimulating excitatory effect during the absorption phase, parallel to the increase in BAC. The reverse pattern in the first part of the elimination phase infers a decrease in cerebral activation reflecting the sedative, depressant action of alcohol in this phase. The effects observed in the last trial, to a certain extent interpreted as stimulating, were simultaneous with the beginning of the post-alcohol hangover phase.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Breaking up sitting enhances neurocognitive function which is associated with improved postprandial glucose regulation in healthy adults: A randomized crossover study.
Physiol Behav
March 2025
Department of Physical Education and Sport Sciences, National Taiwan Normal University, Taipei, Taiwan; Institute for Research Excellence and Learning Sciences, National Taiwan Normal University, Taipei, Taiwan. Electronic address:
Article Synopsis
- The study explores how breaking up prolonged sitting with short walking intervals affects blood sugar levels, attention, and cognitive processing.
- Participants completed tasks after either sitting continuously or walking intermittently, with results showing improved brain activity (P3 amplitude) and lower blood glucose levels when walking was included.
- These findings suggest that incorporating movement during long periods of sitting can enhance cognitive function and help manage blood sugar levels effectively.
Electrophysiological correlates of temporal numerosity adaptation.
Front Neurosci
March 2024
Department of Neuroscience, Psychology, Pharmacology and Child Health, University of Florence, Florence, Tuscany, Italy.
Introduction: Much research has revealed the human visual system is capable to estimate numerical quantities, rapidly and reliably, in both the spatial and the temporal domain. This ability is highly susceptible to short-term plastic phenomena related to previous exposure to visual numerical information (i.e.
View Article and Find Full Text PDFNeural basis of the attention bias during addiction stroop task in methamphetamine-dependent patients with and without a history of psychosis: an ERP study.
Front Psychol
June 2023
Department of Addiction Medicine, Shenzhen Clinical Research Center for Mental Disorders, Shenzhen Kangning Hospital, Shenzhen Mental Health Center, the School of Mental Health of Southern University of Science and Technology, Shenzhen University, Anhui Medical University, and Jining Medical College, Shenzhen, China.
Background: Attentional bias plays an important role in sustaining various types of drug addiction. No prior studies examined methamphetamine (MA)-associated psychosis (MAP) relationships between ERP time course and performance on an addiction Stroop task in MA abusers. The aim of the present study was to determine whether MA abusers with (MAP+) or without (MAP-) psychosis exhibit alterations of the ERP during the addiction Stroop task.
View Article and Find Full Text PDFEffects of cognitive demand during acute exercise on inhibitory control and its electrophysiological indices: A randomized crossover study.
Physiol Behav
June 2023
Department of Physical Education and Sport Sciences, National Taiwan Normal University, Taipei, Taiwan; Institute for Research Excellence and Learning Science, National Taiwan Normal University, Taipei, Taiwan. Electronic address:
The aim of this study was to examine the effects of cognitive demand during acute exercise on the behavioral and electrophysiological correlates of inhibitory control. In a within- participants design, 30 male participants (age range = 18-27 years) performed 20-min sessions of high cognitive-demand exercise (HE), low cognitive-demand exercise (LE), and an active control (AC) on separate days in a randomized order. A moderate-to-vigorous intensity interval step exercise was used as the exercise intervention.
View Article and Find Full Text PDFPrestimulus oscillatory brain activity interacts with evoked recurrent processing to facilitate conscious visual perception.
Sci Rep
December 2022
Center for Cognitive Neuroscience, Duke Institute for Brain Sciences, Duke University, Durham, NC, 27708, USA.
We investigated whether prestimulus alpha-band oscillatory activity and stimulus-elicited recurrent processing interact to facilitate conscious visual perception. Participants tried to perceive a visual stimulus that was perceptually masked through object substitution masking (OSM). We showed that attenuated prestimulus alpha power was associated with greater negative-polarity stimulus-evoked ERP activity that resembled the visual awareness negativity (VAN), previously argued to reflect recurrent processing related to conscious perception.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!