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Assessments of genetic diversity, structure, history, and effective population size ( ) are critical for the conservation of imperiled populations. The lesser prairie-chicken () has experienced declines due to habitat loss, degradation, and fragmentation in addition to substantial population fluctuations with unknown effects on genetic diversity. Our objectives were to: (i) compare genetic diversity across three temporally discrete sampling periods (2002, 2007-2010, and 2013-2014) that are characterized by low or high population abundance; (ii) examine genetic diversity at lek and lek cluster spatial scales; (ii) identify potential bottlenecks and characterize genetic structure and relatedness; and (iii) estimate the regional .
View Article and Find Full Text PDFIdentification and characterization of multiple novel viruses in fecal samples of cormorants.
Front Vet Sci
January 2025
Department of Microbiology, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, China.
Introduction: Cormorants, as protected wild animals by the State Forestry Administration of China, have a broad distribution across China. Previous studies have shown that they can be infected with multiple viruses in the , , , and families. There is limited knowledge about the other viruses that cormorants may carry and infect.
View Article and Find Full Text PDFBlockade of Src signaling prevented stemness gene expression and proliferation of patient-derived gastric cancer stem cells.
Tzu Chi Med J
September 2024
School of Medicine, Tzu Chi University, Hualien, Taiwan.
Objectives: Gastric cancer (GC) is one of the most malignant tumors. Mounting studies highlighted gastric cancer stem cells (GCSCs) were responsible for the failure of treatment due to recurrence and drug resistance of advanced GC. However, targeted therapy against GCSC for improving GC prognosis suffered from lack of suitable models and molecular targets in terms of personalized medicine.
View Article and Find Full Text PDFPhenotypic and genetic extended spectrum beta lactamase profiles of bacterial isolates from ICU in tertiary level hospital in Kenya.
F1000Res
January 2025
Department of Human Pathology, University of Nairobi, Nairobi, Nairobi County, Kenya.
Background: Bacterial infections in the Intensive Care Units are a threat to the lives of critically ill patients. Their vulnerable immunity predisposes them to developing bacteria-associated sepsis, deteriorating their already fragile health. In the face of increasing antibiotics resistance, the problem of bacterial infection in ICU is worsening.
View Article and Find Full Text PDFPrevalence and characterization of IncQ1α-mediated multi-drug resistance in Isolated from pigs in Kunming, Yunnan, China.
Front Microbiol
January 2025
Yunnan Joint International R&D Center of Veterinary Public Health, College of Veterinary Medicine, Yunnan Agricultural University, Kunming, China.
Background: is a conditionally pathogenic bacterium that is inherently resistant to polymyxin and tigecycline, largely due to antibiotic resistance genes (ARGs). These ARGs can be horizontally transferred to other bacteria, raising concerns about the Inc plasmid-mediated ARG transmission from , which poses a serious public health threat. This study aims to investigate the presence of Inc plasmid types in pig-derived in Kunming, Yunnan, China.
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