Severity: Warning
Message: file_get_contents(https://...@pubfacts.com&api_key=b8daa3ad693db53b1410957c26c9a51b4908&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
Filename: helpers/my_audit_helper.php
Line Number: 176
Backtrace:
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 176
Function: file_get_contents
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 250
Function: simplexml_load_file_from_url
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3122
Function: getPubMedXML
File: /var/www/html/application/controllers/Detail.php
Line: 575
Function: pubMedSearch_Global
File: /var/www/html/application/controllers/Detail.php
Line: 489
Function: pubMedGetRelatedKeyword
File: /var/www/html/index.php
Line: 316
Function: require_once
Discrimination between histologically confirmed benign and malignant gastric ulcerations was studied, using an oncofetal antigen (FSA) as the parameter of malignant transformation. In chronic gastric ulcer FSA could be found in 54.2% as compared with 20.0% in duodenal ulcer patients. 91.1% of gastric cancers were FSA positive. A current epidemiological study on a non-selected population gives 8.8% FSA secretors. The study supports the earlier conception that chronic gastric ulcer must be considered a precursor of cancer, and indicates the need, especially in cases showing FSA secretion, for active surgical therapy or a long-term follow-up with endoscopic biopsies.
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