Material from hearts known to have had recent myocardial infarction and biopsies of dog hearts subjected to an experimental procedure producing ischaemic injury, were examined by polarising microscopy. A technique which depends on the relaxation of sarcomeres on ischaemic areas of myocardia was used and assessed for its value in the diagnosis of early myocardial infarction. We found no statistically significant difference in sarcomere lengths in ischaemic and control heart muscle in man. The dog study failed to show changes with a study period of up to 2 h after ligation. We do not support the suggestion that sarcomere length is a useful measurement in the demonstration of early myocardial ischaemic injury in man.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/BF02215985 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Interventricular septal dissection secondary to acute inferior myocardial infarction: case series and literature review.
J Cardiothorac Surg
January 2025
Echocardiography and Vascular Ultrasound Center, The First Affiliated Hospital, Zhejiang University School of Medicine, 79 Qingchun Road, Hangzhou, 310003, China.
Background: Interventricular septal dissection is a critical disease characterized by the separation of the intraventricular septum into two layers, forming an intermediate layer with a cystic cavity that communicates with the root of the aorta or ventricle. It has low morbidity and high mortality rates.
Case Presentation: Case 1: A 58-year-old male with a history of hypertension and smoking presented to a local hospital due to chest tightness and pain for 4 days.
Synaptotagmin-1 attenuates myocardial programmed necrosis and ischemia/reperfusion injury through the mitochondrial pathway.
Cell Death Dis
January 2025
Key Laboratory of Cellular Physiology at Shanxi Medical University, Ministry of Education, and the Department of Physiology, School of Basic Medicine, Shanxi Medical University, Taiyuan, China.
Programmed necrosis/necroptosis greatly contributes to the pathogenesis of cardiac disorders including myocardial infarction, ischemia/reperfusion (I/R) injury and heart failure. However, the fundamental mechanism underlying myocardial necroptosis, especially the mitochondria-dependent death pathway, is poorly understood. Synaptotagmin-1 (Syt1), a Ca sensor, is originally identified in nervous system and mediates synchronous neurotransmitter release.
View Article and Find Full Text PDFRole of Antidepressants in Acute Coronary Syndrome: An Evidence-Based Case Report.
Acta Med Indones
October 2024
1. Division of Psychosomatic and Palliative, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia. 2. Clinical Epidemiology in Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
Background: Acute coronary syndrome (ACS) and depression are related to each other. Detection and proper treatment of these conditions can improve functional ability and quality of life. However, there is still controversy in this population regarding the use, safety, and efficacy of antidepressant pharmacotherapy.
View Article and Find Full Text PDF[Predictive model for ejection fraction improvement at one year in patients with acute ST-segment elevation myocardial infarction complicated with heart failure with reduced ejection fraction].
Zhonghua Yi Xue Za Zhi
January 2025
Ningbo Hangzhou Bay Hospital(Ningbo Branch of Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai),Ningbo315336, China.
To develop a predictive model for improvement of ejection fraction 1 year after heart failure with reduced ejection fraction (HFrEF) following acute ST-segment elevation myocardial infarction (STEMI). This nested case-control study included STEMI patients diagnosed with HFrEF from a prospective multicenter multimodality imaging cohort between August 2014 and March 2021. Based on the improvement of left ventricular ejection fraction (LVEF) at baseline and 1-year follow-up, the patients were classified into the heart failure with improved ejection fraction (HFimpEF) group and the persistent HFrEF group.
View Article and Find Full Text PDFComfort and patient activation in patients with myocardial infarction: A cross-sectional study.
Appl Nurs Res
February 2025
Akdeniz University Nursing Faculty, Antalya, Turkey. Electronic address:
Aims: To examine comfort and patient activation, affecting factors, and the relationship between comfort and patient activation in patients with myocardial infarction.
Background: Comfort is an important requirement for managing the treatment and patients' well-being and patient activation improves patient engagement. Assessment of comfort, patient activation and associated factors are important to reduce complications and ensure adherence.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!