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Protocol for the development of a guideline on post-extubation respiratory support for mechanically ventilated patients in the ICU.
BMJ Open
January 2025
Evidence based medicine center, Lanzhou University, Lanzhou, Gansu, China.
Unlabelled: Prophylactic respiratory support for patients after extubation is effective in improving their outcomes and prognosis. However, the optimal post-extubation respiratory support for different populations and disease types of mechanically ventilated patients remains controversial, and there is a lack of detailed, multidisciplinary, evidence-based recommendations for clinical application.
Methods And Analysis: This protocol strictly follows the development process outlined in the WHO Handbook for Guideline Development and Guidelines 2.
VARX Granger analysis: Models for neuroscience, physiology, sociology and econometrics.
PLoS One
January 2025
Department of Electrical and Computer Engineering, University of Maryland, College Park, MD, United States of America.
Complex systems, such as in brains, markets, and societies, exhibit internal dynamics influenced by external factors. Disentangling delayed external effects from internal dynamics within these systems is often difficult. We propose using a Vector Autoregressive model with eXogenous input (VARX) to capture delayed interactions between internal and external variables.
View Article and Find Full Text PDFThe Effects of Resonance Frequency Breathing on Cardiovascular System and Brain-Cardiopulmonary Interactions.
Appl Psychophysiol Biofeedback
January 2025
The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, No.28, Xianning West Road, Xi'an, Shaanxi, 710049, P. R. China.
Resonance frequency (RF) is characterized as the specific frequency at which a system, equipped with delayed self-correction or negative feedback mechanisms, exhibits maximal amplitude oscillations in response to an external stimulus of a particular frequency. Emerging evidence suggests that the cardiovascular system has an inherent RF, and that breathing at this frequency can markedly enhance health and cardiovascular function. However, the efficacy of resonance frequency breathing (RFB) and the specific responses of the cardiovascular, respiratory, and central nervous systems during RFB remain unclear.
View Article and Find Full Text PDFCorrelation of Preclinical Imaging Modalities and Immunohistochemistry for Tumor Hypoxia and Vasculature.
In Vivo
December 2024
School of Physics, Mathematics and Computing, The University of Western Australia, Perth, Australia.
Background/aim: Tumors exhibit impaired blood flow and hypoxic areas, which can reduce the effectiveness of treatments. Characterizing these tumor features can inform treatment decisions, including the use of vasculature modulation therapies. Imaging provides insight into these characteristics, with techniques varying between clinical and preclinical settings.
View Article and Find Full Text PDFAn artificial intelligence application to predict prolonged dependence on mechanical ventilation among patients with critical orthopaedic trauma: an establishment and validation study.
BMC Musculoskelet Disord
December 2024
Department of Orthopedics, Hainan Hospital of PLA General Hospital, Hainan, China.
Background: Prolonged dependence on mechanical ventilation is a common occurrence in clinical ICU patients and presents significant challenges for patient care and resource allocation. Predicting prolonged dependence on mechanical ventilation is crucial for improving patient outcomes, preventing ventilator-associated complications, and guiding targeted clinical interventions. However, specific tools for predicting prolonged mechanical ventilation among ICU patients, particularly those with critical orthopaedic trauma, are currently lacking.
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