Post-operative radiotherapy of supraglottic carcinoma, because of the high risk of lymph-nodal metastases, should include irradiation of the primary tumour as well as regional lymph-nodes (jugular chain, posterior cervical. supraclavicular, submental and submaxillary triangle nodes). Taking into account the anatomically complex region to be irradiated and the critical organs present within the areas involved, the authors present a treatment plan that provides the neck irradiation through three 60Co fields: Two posterior oblique and a posterior one with median lead block in correspondence to the spinal cord. The isodose curves (at jaw level, at the medium plane of the neck and at clavear level) show that the required dose distribution has been achieved by safeguarding of radiation tissue tolerance of medulla. The authors conclude that only the adoption of a "different" procedure, i.e. outwith of any reciprocal relation "portal-target", has permitted the overcoming of anatomo-clinical problems linked with the region to be irradiated. The authors believe that the adopted methodology, the only acceptable in case of irradiation of anatomically complex and articulate regions, can be also extended to simple cases where immediate and intuitive solution is not always the most appropriate, one.
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Laryngoscope Investig Otolaryngol
February 2025
Introduction: Castleman disease (CD) refers to a heterogeneous group of lymphoproliferative disorders, which rarely involves the larynx. Our goal in this study is to elucidate the clinical presentation, diagnostic techniques, and treatment methods of laryngeal CD through a scoping review and the addition of a new case.
Methods: Due to limited existing literature, we employed a mixed methodology for review.
Anaesthesia
January 2025
The Christie NHS Foundation Trust, Manchester, UK.
Introduction: Radiotherapy is currently used in approximately one-third of children with cancer. Treatments are typically received as weekday outpatient appointments over 3-6 weeks. The treatment is painless but requires a still, co-operative patient who can lie alone in set positions, facilitated by the use of immobilisation devices, for up to 1 h.
View Article and Find Full Text PDFLin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
January 2025
To investigate optimal treatment strategy for pT3N0 laryngeal squamous cell carcinoma(SCC). A retrospective study of 150 patients with pT3N0 laryngeal SCC treated in the First Affiliated Hospital of Chongqing Medical University was performed. The efficacies of partial laryngectomy and total laryngectomy, as well as surgery alone and postoperative radiotherapy were evaluated.
View Article and Find Full Text PDFEur Arch Otorhinolaryngol
December 2024
King Hussein Cancer Center, Medical Oncology Department, Amman, Jordan.
Purpose: Over the last 40 years, there has been an unusual trend where, even though there are more varied treatments, survival rates have not improved much. Our study used survival analysis and machine learning (ML) to investigate this odd situation and to improve prediction methods for treating non-metastatic LSCC.
Methods: The surveillance, epidemiology and end results (SEER) database provided the data used for this study's analysis.
Iran J Otorhinolaryngol
January 2024
Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
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