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Time trend and identification of risk areas for physical disability due to leprosy in Brazil: An ecological study, 2001-2022.
BMC Infect Dis
March 2025
University of Pernambuco (UPE), BR 203, Km 2, s/n, Petrolina, Pernambuco, 328-903, Brazil.
Background: Leprosy is a chronic infectious disease that affects the peripheral nerves, leading to neurological damage and physical disability. This study analyzed the temporal trend in the rate of new leprosy cases with grade 2 physical disability in Brazil and identified spatial clusters of risk for physical disability.
Methods: This is an ecological study of all new cases of leprosy with grade 2 physical disability (G2D) at diagnosis between 2001 and 2022 in Brazil, macro-regions, states and municipalities.
Insights into leprosy epidemiology from an isolated population located in the Brazilian Amazon.
Sci Rep
February 2025
Graduate Program in Health Sciences, School of Medicine and Life Sciences, Pontifícia Universidade Católica do Paraná, Curitiba, PR, Brazil.
Leprosy, a chronic infectious disease caused mainly by Mycobacterium leprae (M. leprae), is still an important public health problem in countries such as Brazil and India. Here, we estimate key epidemiological parameters in the Prata Village, a unique, hyper-endemic, former leprosy colony isolated in the Brazilian Amazon.
View Article and Find Full Text PDFPersistently high TB prevalence in Nairobi County neighbourhoods, 2015-2022.
PLOS Glob Public Health
February 2025
Department of Medicine, University of Washington, Seattle, Washington, United States of America.
National and sub-national population-based surveys, when performed at intervals, may assess important changes in TB prevalence. In 2022 we re-surveyed nine Nairobi County neighbourhoods that were previously surveyed in 2015. We aimed to determine pulmonary TB prevalence, compare prevalence to 2015 estimates, and evaluate changes in risk groups.
View Article and Find Full Text PDFDiagnosis of Mycobacterium leprae in free-living animals in a hyperendemic area in Brazil.
Vet Microbiol
March 2025
Federal University of Mato Grosso, Faculty of Veterinary Medicine, Microbiology and Molecular Biology Department, Brazil.
Mycobacterium leprae (M. leprae) is a globally distributed intracellular pathogen that causes human leprosy. For many years, M.
View Article and Find Full Text PDFThe Neglected Tropical Disease Non-Governmental Organization Network: The role of a global health network in an evolving global health landscape.
PLOS Glob Public Health
January 2025
The Leprosy Mission Nepal, Kathmandu, Nepal.
The Neglected Tropical Diseases NGO Network (NNN) was established in 2009 to bring together non-governmental organizations (NGOs) working towards the control and elimination of neglected tropical diseases (NTDs). In response to the evolving landscape of global health and the increasing focus on equity, the NNN conducted a membership analysis in 2021. This analysis aimed to assess the network's composition and connectivity, revealing significant insights into its current structure and areas for improvement.
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