The presence of mucociliary dysfunction in bronchial asthma is suggested by clinical observations and has been confirmed by pathologic and physiologic studies. Since mucociliary dysfunction may play a considerable role in the pathophysiology of bronchial asthma, currently available therapeutic measures which enhance mucous transport should be included in the treatment plan. It is expected that a better understanding of the underlying mechanisms will ultimately result in the development of more potent pharmacologic agents capable of improving abnormal mucociliary function.
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| http://dx.doi.org/10.3109/02770908109118307 | DOI Listing |
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