In this series the results of limbal trephination were excellent in patients over 35 years of age, particularly those in the 50 and older age group, with chronic open-angle and chronic angle-closure glaucoma. Results were poor in younger age groups and in those with secondary glaucoma, particularly when it was associated with inflammatory disease.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/00004397-198102110-00005 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
ROCK Inhibitor Enhances Neurite Outgrowth In Vitro and Corneal Sensory Nerve Reinnervation In Vivo.
Invest Ophthalmol Vis Sci
October 2024
Department of Anatomy and Cell Biology, GW School of Medicine and Health Sciences, Washington DC, United States.
Article Synopsis
- The study investigates the role of rho kinase (ROCK) inhibitors in promoting the health of corneal nerves and their potential effect on nerve regeneration after injury.
- Researchers analyzed integrin and extracellular matrix expression in mouse neurons and explored how RI treatment influences neurite growth both in lab cultures and in live mice following injuries.
- Results showed that specific integrins were present on neuron growth structures, and RI treatment enhanced nerve growth in vitro and improved sensory nerve recovery in vivo after injury.
Substrate Stiffness Modulates Stemness and Differentiation of Rabbit Corneal Endothelium Through the Paxillin-YAP Pathway.
Invest Ophthalmol Vis Sci
March 2024
Department of Ophthalmology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Purpose: To explore the role of substrate stiffness and the mechanism beneath corneal endothelial cells' (CECs') stemness maintenance and differentiation.
Methods: CECs were divided into central zone (8 mm trephined boundary) and peripheral zone (8 mm trephined edge with attached limbal). Two zones were analyzed by hematoxylin-eosin staining and scanning electron microscopy for anatomic structure.
Sutureless lamellar keratoplasty with lenticule from small incision lenticule extraction for treating limbal dermoid: A case report.
Exp Ther Med
February 2024
Department of Ocular Surface and Refraction, Heji Hospital Affiliated to Changzhi Medical College, Changzhi, Shanxi 046000, P.R. China.
Article Synopsis
- This study discusses a new surgical technique for treating a superficial limbal dermoid using lamellar keratoplasty without stitches, incorporating an allogenic lenticule from a small incision method.
- The technique involves careful removal of the dermoid and attaching a stromal lenticule directly to the implant bed, secured with a bandage contact lens instead of sutures or glue.
- Postoperative results were positive, with improvement noted in corneal thickness, curvature, and patient satisfaction over three months, suggesting this method may be advantageous compared to traditional lamellar keratoplasty.
Corneal and Limbal Alkali Injury Induction Using a Punch-Trephine Technique in a Mouse Model.
J Vis Exp
August 2023
Department of Ophthalmology, Stanford University School of Medicine;
The cornea is critical for vision, and corneal healing after trauma is fundamental in maintaining its transparency and function. Through the study of corneal injury models, researchers aim to enhance their understanding of how the cornea heals and develop strategies to prevent and manage corneal opacities. Chemical injury is one of the most popular injury models that has extensively been studied on mice.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!