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The review presents the modern concepts on biochemical mechanisms of processes, that result in comatose states (CS), with emphasis on the search of new therapeutic approaches. CS of various origin causes severe suppression of brain cells functioning and stable unconsciousness. Numerous reasons of various CS are classified into two main groups: primary brain damages (ischemia, tumor, trauma) and secondary damages originating from system injuries in the body (endocrine, toxic e.
View Article and Find Full Text PDF[Clinical scoring scales for brain injury].
Rev Stomatol Chir Maxillofac
September 2006
Service de Chirurgie Maxillo-faciale et Stomatologie, CHU de Besançon, France.
The development of data processing techniques has enabled the establishment of large databanks on brain injury. Clinical features are described with clinical scoring scales, the main one being the Glasgow Coma Scale. Three types of patient response are analyzed: eye opening, oral answers, active muscular reaction.
View Article and Find Full Text PDF[The limits of intensive care in craniocerebral trauma].
Zentralbl Chir
June 1994
Klinik für Neurochirurgie, Universität Köln.
Cerebral lesions of variable severity lead to systemic and intracranial reactions. These create secondary brain damage due to hypoxia and ischemia. The causes as well as the sequelae of secondary brain damage necessitate long-term intensive care treatment with high technical and personal expenditure.
View Article and Find Full Text PDF[Prognostic assessment and diagnosis of brain death on the intensive care unit].
Klin Anasthesiol Intensivther
September 1994
The Western Neuro Sensory Stimulation Profile: a tool for assessing slow-to-recover head-injured patients.
Arch Phys Med Rehabil
February 1989
University of California, Irvine Medical Center, Orange.
The Western Neuro Sensory Stimulation Profile (WNSSP) was developed to assess cognitive function in severely impaired head-injured adults (Rancho levels II-V) and to monitor and predict change in slow-to-recover patients. Slow-to-recover patients are those who remain at Rancho levels II and III for extended periods of time and are candidates for sensory stimulation programs. Although sensory stimulation is considered beneficial, its utility has not been documented, partly because of the absence of formal measurement tools.
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