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Analysis of the morbidity characteristics and related factors of pulmonary nodules in patients with type 2 diabetes mellitus: a retrospective study.
BMC Endocr Disord
January 2025
Dongzhimen Hospital, Affiliated to Beijing University of Chinese Medicine, Beijing, 100700, China.
Objective: To analyze the characteristics of pulmonary nodules (PNs) and related influencing factors in patients with type 2 diabetes mellitus (T2DM).
Methods: Retrospectively analyzed the clinical and biochemical characteristics of 224 patients with PNs and 488 patients with non-PNs in patients with T2DM, and compared the clinical data of 72 patients with large nodules (≥ 5 mm) and 152 patients with small nodules (< 5 mm) in the pulmonary nodules (PNs) group.
Results: Compared to the non-PNs group, the PNs Patients in the group had a longer duration of diabetes, higher age, serum creatinine (SCR), blood urea nitrogen (BUN) and the lower albumin (ALB) and body mass index (BMI); women, diabetic retinopathy (DR), diabetic peripheral neuropathy (DPN), and estimated glomerular filtration rate (eGFR) < 60 ml/min1.
Hyperuricemia prevalence and its risk factors in uremic patients undergoing maintenance hemodialysis.
BMC Nephrol
January 2025
Department of Nephrology, Jinshan Hospital Affiliated to Fudan University, Shanghai, China.
Background: To explore the prevalence of hyperuricemia and its associated factors in uremic patients undergoing maintenance hemodialysis (MHD).
Methods: Two hundred two uremic patients undergoing MHD for ≥ 3 months, in Jinshan Hospital, Fudan University, were enrolled. Pre-dialysis blood samples were tested during March 1st, 2023 to April 30th, 2023.
Dexmedetomidine alleviates acute kidney injury in a rat model of veno-arterial extracorporeal membrane oxygenation.
Intensive Care Med Exp
January 2025
Department of Cardiac Surgery, Lanzhou University Second Hospital, Lanzhou University, No. 80, Cuiyingmen, Chengguan District, Lanzhou, 730030, China.
Background: Although extracorporeal membrane oxygenation (ECMO) is an effective technique for life support, the incidence of acute kidney injury (AKI) during ECMO support remains high. Dexmedetomidine (DEX), which has been widely used for sedation during ECMO, possesses several properties that help reduce the occurrence of AKI. This study aimed to investigate the protective effect of DEX on kidney function during ECMO.
View Article and Find Full Text PDFOsmotolerance reflected in mitochondrial respiration of Mytilus populations from three different habitat salinities.
Mar Environ Res
January 2025
Marine Biology, Institute for Biological Sciences, University of Rostock, Albert-Einstein-Strasse 3, D - 18059, Rostock, Germany; Department of Maritime Systems, Interdisciplinary Faculty, University of Rostock, Albert-Einstein-Strasse 21, D-18059, Rostock, Germany.
Mussels from the Mytilus edulis species complex experience a salinity gradient from the North Sea into the Baltic Proper ranging from 32 to 5. As osmoconformers, they adjust their internal osmolarity to match that of their surroundings, which presents a significant challenge to the metabolic machinery, including their mitochondria. We hypothesized that the osmotic optima for the mitochondrial function of mussels matches the prevailing habitat salinity and is accompanied by a population specific metabolite profile.
View Article and Find Full Text PDFSemi-field studies on biochemical markers of honey bee workers (Apis mellifera) after exposure to pesticides and their mixtures.
PLoS One
January 2025
Department of Bees Breeding, Institute of Animal Husbandry and Breeding, Wroclaw University of Environmental and Life Sciences, Wroclaw, Poland.
Article Synopsis
- Many pesticides used in agriculture can accumulate in the environment, exposing bees to multiple substances simultaneously, which is not commonly studied in research.
- The study focused on the chronic effects of pesticide mixtures on honey bee worker's hemolymph, using concentrations found in their natural environment.
- Results showed that acetamiprid decreased urea levels significantly, glyphosate had little effect, and tebuconazole, despite being considered safe, caused notable changes in several biochemical markers, indicating a need for further research on fungicides' impact on bees.
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