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Twist of Fate: Diagnosing and Managing Gallbladder Volvulus in an Elderly Patient.
Cureus
February 2025
Colorectal Surgery, James Cook University Hospital, Middlesbrough, GBR.
Gallbladder volvulus (GV) is a rare surgical emergency characterized by the twisting of the gallbladder around its mesentery, leading to vascular compromise and gangrene. It is often misdiagnosed as acute gangrenous cholecystitis due to overlapping symptoms, making preoperative diagnosis challenging. Definitive identification is typically made intraoperatively.
View Article and Find Full Text PDFCoupled Influence of Magnetic Biochar and Solution Chemistries on Retention and Release of Nanoplastics in Porous Media.
Int J Mol Sci
February 2025
School of Resources, Environment and Materials, Guangxi University, Nanning 530004, China.
Magnetic biochar (MBC), as an environmentally friendly material, has been extensively used for the remediation of soil and groundwater contamination. The retention and release of nanoplastics (NPs) with carboxyl (NPs-COOH) or amino functionalization (NPs- NH) in saturated porous media were investigated under varying conditions of ionic strength (IS), MBC addition, humic acid (HA) concentration, and cation types. The reversible and irreversible retention of NPs was examined by altering the IS, increasing the solution pH, and inducing cation exchange.
View Article and Find Full Text PDFTheoretical Study on the Metabolic Mechanism of Heptachlor in Human Cytochrome P450 Enzymes.
Int J Mol Sci
February 2025
Institute of Theoretical Chemistry, Jilin University, Changchun 130021, China.
Heptachlor (HEP) is an insecticide metabolized by cytochrome P450 (CYP) enzymes in the human liver, resulting in the formation of heptachlor epoxide (HEPX). HEPX can persist in the human body for a long duration. Therefore, it can be extremely harmful.
View Article and Find Full Text PDFThe Essential Role of Mitochondrial Dynamics in Viral Infections.
Int J Mol Sci
February 2025
College of Veterinary Medicine, Inner Mongolia Agricultural University, Hohhot 010018, China.
Mitochondria are dynamic organelles that play crucial roles in energy production, metabolic balance, calcium homeostasis, apoptosis, and innate immunity, and are key determinants of cell fate. They are also targets for viral invasion of the body. Many viral proteins target mitochondria, controlling mitochondrial morphology, metabolism, and immune response, thereby achieving immune evasion, promoting their proliferation, and accelerating the infection process.
View Article and Find Full Text PDFThe Dark Side of the Moon: A Good Adoption Rate Conceals the Unsolved Ethical Problem of Never-Adopted Dogs.
Animals (Basel)
February 2025
Canile Sovrazonale, ASL Roma 3, 00148 Roma, Italy.
The no-kill policy for domestic dogs, adopted in Italy in 1991, reflects a growing interest in animal welfare and increases the chances of dogs being adopted and living with a family. However, unadoptable dogs must spend their entire lives in shelters. This paper reports the adoption numbers from the 'Muratella' shelter (Rome) during the periods 2012-2016 (first period) and 2018-2022 (second period), illustrating the outcomes of the no-kill policy in a large metropolitan area.
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