Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/0042-6822(81)90004-0 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Nation-wide surveillance of tick (Acari: Ixodidae) infestations of humans in Singapore.
Ticks Tick Borne Dis
January 2025
Department of Microbiology and Immunology, Immunology Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Electronic address:
Ticks are an increasingly important threat to public health in Southeast Asia, due to the role of many tick species as parasites of humans and as vectors of zoonotic pathogens. Singapore is a densely populated Southeast Asian nation with a rich tick fauna and a significant mosaic of city and greenspace. However, apart from occasional case reports, the human-biting ticks in Singapore have received little attention from researchers.
View Article and Find Full Text PDFThe actin-based motility effectors RickA and Sca2 contribute differently to cell-to-cell spread and pathogenicity.
mBio
January 2025
Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California, USA.
is an obligate intracellular, tick-borne bacterial pathogen that can cause eschar-associated rickettsiosis in humans. invades host cells, escapes from vacuoles into the cytosol, and undergoes two independent modes of actin-based motility mediated by effectors RickA or Sca2. Actin-based motility of enables bacteria to enter protrusions of the host cell plasma membrane that are engulfed by neighboring host cells.
View Article and Find Full Text PDF: West Nile virus (WNV) is a rapidly growing problem worldwide. The lack of emergency treatment and a safe licensed vaccine against WNV allows the virus to cause sporadic outbreaks of human disease, including fatal cases. Formalin-inactivated vaccines have been used for a long time and have been shown to be very safe and effective, especially in susceptible populations.
View Article and Find Full Text PDFSeroprevalence and risk factors for Crimean-Congo hemorrhagic fever virus exposure among febrile patients in northern Tanzania.
Trop Med Int Health
January 2025
Programme in Emerging Infectious Diseases, Duke-National University of Singapore Medical School, Singapore, Singapore.
Background: Crimean-Congo hemorrhagic fever is a tick-borne zoonotic disease that may be severe and is present in many African countries. We aimed to understand the seroprevalence and risk for Crimean-Congo hemorrhagic fever virus in Tanzania by testing archived serum samples from patients enrolled in a prospective cohort study.
Methods: We prospectively enrolled febrile inpatients and outpatients from 2012 through 2014 at two referral hospitals in northern Tanzania.
Limitations of a proper SFTSV mouse model using human C-type lectin receptors.
Front Microbiol
December 2024
Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea.
Severe fever with thrombocytopenia syndrome virus (SFTSV) is a tick-borne virus with a human mortality rate of up to 30%, posing a significant threat to public health. However, the lack of suitable research models has impeded the development of effective human vaccines. In this study, we engineered transgenic mice (3xTg) using a novel construct that simultaneously expresses three C-type Lectin receptors, identified as critical SFTSV entry receptors.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!