Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Automatic monitoring and on-line chiral separation of chiral drug synthesis.
J Chromatogr A
January 2025
College of Chemistry and Materials Engineering, Bohai University, Jinzhou, Liaoning Province 121013, PR China.
Chiral synthesis of single chiral drugs offers high efficiency, controllable costs, and excellent enantioselectivity, making it crucial in the pharmaceutical industry. A significant number of studies on chiral drug synthesis primarily focuses on the design and synthesis of innovative chiral catalysts and ligands with extremely high selectivity, as well as the development of new methods and strategies. Nonetheless, the on-line monitoring of chiral drug synthesis and its underlying mechanisms remain obscure.
View Article and Find Full Text PDFA versatile and automatic on-line screening method: Transverse diffusion of laminar flow profiles-based capillary electrophoresis for exploring PTP1B inhibitors in natural products.
J Chromatogr A
January 2025
KU Leuven - University of Leuven, Pharmaceutical Analysis, Department of Pharmaceutical and Pharmacological Sciences, O&N2, PB 923, Herestraat 49 3000 Leuven, Belgium. Electronic address:
Natural products (NPs) play an important role in drug discovery and drug development due to their diverse chemical properties and biological activities. In the present work, an on-line capillary electrophoresis (CE) method was developed and applied to screen protein tyrosine phosphatase 1B (PTP1B) inhibitors in NPs. As a generic technique, transverse diffusion of laminar flow profiles (TDLFP) was utilized to mix all reactants in the capillary for on-line enzymatic reaction.
View Article and Find Full Text PDFDevelopment of a new spectral database of photo-induced pesticide compounds for an automatic monitoring and identification system.
Anal Chim Acta
January 2025
Laboratoire OPTIMAG, Université de Brest, 6 Av. Victor Le Gorgeu, 29285, Brest, Cedex, France. Electronic address:
Article Synopsis
- The widespread use of pesticides necessitates effective monitoring of surface water quality, but traditional methods are complex, costly, and time-consuming.
- The proposed solution involves a novel photoinduced fluorescence method paired with a lightweight database that simplifies pesticide identification by using combined spectra.
- This system enables on-line monitoring and accurate identification of pesticides in surface water, making it accessible for untrained users and demonstrating promising analytical performance.
MarblingPredictor: A software to analyze the quality of dry-cured ham slices.
Meat Sci
March 2025
Institute of Agrifood Research and Technology (IRTA), Food Technology, Finca Camps i Armet, Girona 17121, Spain. Electronic address:
Dry-cured ham is a traditional Mediterranean meat product consumed throughout the world. This product is very variable in terms of composition and consumer's acceptability is influenced by different factors, among others, visual intramuscular fat and its distribution across the slice, also known as marbling. On-line inter and intramuscular fat evaluation and marbling assessment is of interest for classification purposes at the industry.
View Article and Find Full Text PDFHome-based online line bisection test detects visuo-spatial neglect and pseudoneglect in Parkinson's disease.
Parkinsonism Relat Disord
January 2025
Laboratory of Cognitive Neuroscience, Neuro-X Institute, Faculty of Life Sciences, Swiss Federal Institute of Technology (EPFL), Geneva, Switzerland; Department of Clinical Neurosciences, Faculty of Medicine, University of Geneva, Geneva, Switzerland. Electronic address:
Introduction: Parkinson's Disease (PD) may lead to cognitive symptoms, including visuo-spatial attentional deficits such as unilateral spatial neglect (USN). Although there is some evidence for USN in PD patients, especially in those with left-sided onset of motor-symptoms (LPD), previous studies revealed inconsistent and highly variable results in neglect tasks using line bisection and have not systematically compared LPD with RPD (PD patients with right-sided onset) or healthy controls (HC).
Methods: We designed a fully automatized online web-based line bisection task and tested a group of 170 PD patients (81 RPD, 66 LPD) and 45 HC.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!