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Review: Pathogenesis of canine atopic dermatitis: skin barrier and host-micro-organism interaction.
Vet Dermatol
April 2015
Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, 2015 SW 16th Avenue, Gainesville, FL, 32610, USA.
Background: Canine atopic dermatitis (AD) is a common, genetically predisposed, inflammatory and pruritic skin disease. The pathogenesis of canine AD is incompletely understood.
Objectives: The aim of this review is to provide an in-depth update on the involvement of skin barrier and host-microbiome interaction in the pathogenesis of canine AD.
Oral diagnosis and treatment planning: part 2. Dental caries and assessment of risk.
Br Dent J
July 2012
School of Dentistry, Charles Sturt University, Orange, New South Wales 2800, Australia.
Dental caries or tooth decay may be defined as a dynamic process causing progressive destruction of hard tooth substance (enamel, dentine and cementum) involving demineralisation of the inorganic portion of the tooth, and dissolution of the organic portion. The onset and progression of carious lesions involves multiple host, micro-organism and substrate factors interacting in a continuous flux. The diagnosis of initial lesions remains a challenge for practitioners and, despite numerous studies, the assessment of future caries risk is still based largely on a patient's past caries experience.
View Article and Find Full Text PDFCandida albicans expresses a fibronectin receptor antigenically related to alpha 5 beta 1 integrin.
Microbiology (Reading)
November 1994
Chair of General Pathology, University of Camerino, Italy.
Cell adhesion molecules, by regulating host-micro-organism interaction, play a major role in the pathogenesis of infectious diseases. The present study was undertaken to investigate the expression of the fibronectin (FN) receptor prototype, alpha 5 beta 1 integrin, on Candida albicans and its involvement in the adhesion to FN. By immunofluorescence and fluorescence activated cell sorter (FACS) analysis, several monoclonal antibodies (mAbs) directed against human alpha 5 or beta 1 integrin subunits, or two different antisera to FN receptor positively stained C.
View Article and Find Full Text PDFSynergistic toxicity of IFN-gamma-producing Escherichia coli K12 cells.
Microb Releases
June 1993
Laboratory Genetics and Biotechnology, Vlaamse Instelling voor Technologisch Onderzoek (VITO), Mol, Belgium.
Genetically modified microorganisms (GMMs) are frequently used as producers of mammalian immunomodulatory proteins, e.g. interferons and interleukins.
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