Several derivatives of (R,S)-2-amino-N-substituted succinimides were synthetized and evaluated in mice against seizures produced by electroshock and pentylenetetrazol. The most active compound against both electroshock- and pentylenetetrazol-induced seizures was (R,S)-N-benzyl-2-(methanesulfamido)succinimide.
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| http://dx.doi.org/10.1002/jps.2600700220 | DOI Listing |
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