The authors present a critical revision of the literature concerning the pathogenic hypotheses and the opinions, during the centuries, about the origin of the deformities caused by amniotic bands. Here they describe two cases of severe deformities caused by amniotic bands which can be classified in types I and V according to Onnipoff and Hall. In the first case the newborn died immediately after the birth: the other one lives in good health after multiple surgical operations. In accordance with the anatomical reports that were found using very specific techniques and methods, the authors are inclined to accept Torpin's hypothesis, which affirms that the initial moment of the series of events which causes the formation of the amniotic bands is the breakage of the amniotic sac.
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Children (Basel)
December 2024
German Center for Fetal Surgery & Minimally Invasive Therapy (DZFT), Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.
Unlabelled: Amniotic band syndrome is a constrictive phenomenon in fetal development that can provoke limb autoamputation, malformation, trunk division, and umbilical cord strangulation. The latter two complications will ultimately lead to fetal demise if left untreated. If detected early enough, select cases may benefit from prenatal resection of the amniotic bands, thus preventing amputation and fetal death.
View Article and Find Full Text PDFCase Rep Obstet Gynecol
December 2024
Department of Obstetrics and Gynecology, Jimma University School of Medicine, Jimma, Ethiopia.
Fetal limb anomaly presentation varies greatly. It can present as amelia (complete absence of skeletal part of one or more limb), meromelia (partial absence of skeletal part of one or more limb), phocomelia (only rudimentary limb formed), and minor limb disorders like polydactyly. The complete absence of the four fetal limbs is extremely rare.
View Article and Find Full Text PDFPaediatr Perinat Epidemiol
December 2024
Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts, USA.
Background: Empirically evaluating the potential impact of recall bias on observed associations of prenatal medication exposure is crucial.
Objective: We sought to assess the effects of exposure misclassification on previous studies of the use of nonsteroidal anti-inflammatory drugs (NSAIDs) in early pregnancy and increased risk of amniotic band syndrome (ABS).
Methods: Using data from the National Birth Defects Prevention Study (NBDPS) on births from 1997 to 2011, we included 189 mothers of infants with ABS and 11,829 mothers of infants without congenital anomalies.
J Hand Surg Asian Pac Vol
December 2024
Department of Plastic, Hand and Reconstructive Microsurgery, Ganga Medical Centre & Hospitals Pvt. Ltd., Coimbatore, Tamil Nadu, India.
Surgical management of constriction ring syndrome (CRS) is individualised due to the heterogenic presentation of the condition. CRS includes constriction rings, acrosyndactyly, nubbins and short digits. Involvement of more than one limb is common and children often need multiple surgeries.
View Article and Find Full Text PDFInt J Gynaecol Obstet
October 2024
Department of Obstetrics and Gynecology, Miyake Clinic, Okayama, Japan.
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