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Background: Pulmonary embolism (PE) is a frequent cause of death. Acute PE may be treated either with full anticoagulation (AC) alone or thrombolytic therapy with systemic tissue-- type-plasminogen-activator (tPA) based on risk assessment. Currently, AC is the standard of care for most patients with intermediate-high-risk PE, with low-dose tPA emerging as an effective alternative.

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Background: Postmenopausal women (PMW) who complete menopause at a late age (55+ years) have lower cardiovascular disease risk than PMW who complete menopause at a normal age (45-54 years). However, the influence of late-onset menopause on vascular endothelial dysfunction is unknown. Moreover, the mechanisms by which a later age at menopause may modulate endothelial function remain to be determined.

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The aim of this systematic review was to summarize the dietary intake of children and adolescents living with HIV and its association with cardiovascular risk factors. PubMed/MEDLINE, Scopus, Web of Science, BIREME and LILACS were searched for original observational studies. The studies were extracted between June and August 2021, in addition to a manual search of references.

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POEMS Syndrome Presenting as First-Time Heart Failure Exacerbation.

JACC Case Rep

January 2025

Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, USA.

We highlight the case of a 40-year-old man who presented with heart failure exacerbation and was ultimately discovered to have POEMS (polyneuropathy, organomegaly, endocrinopathy, monoclonal plasma cell disorder, and skin changes) syndrome.

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Background: Population-based evidence linking sleep characteristics with hearing is limited and how the associations change with age remains unknown. We aim to investigate cross-sectional associations between sleep characteristics and hearing by age in a nationally representative sample of U.S.

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