An extraordinary role of hypothalamic supraoptical nuclei in the ovulation process and luteinizing hormone formation was found out. Morphological studies of the rat ovaries with the affected supraoptical nuclei have shown a sharp inhibition of their function, manifesting in the decreased follicular number of sizes, atresia of primordial follicles, the inhibition of the ovarian ovulatory capacity and luteinizing hormone formation. The ovarian function remained inhibited, despite increased neurosecretory activity of the paraventricular nucleus cells in rats with the affected hypothalamic supraoptic nuclei during hypothermia.
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