Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/s0015-0282(16)45567-6 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Thymic stromal lymphopoietin contributes to endometriotic lesion proliferation and disease-associated inflammation.
J Immunol
February 2025
Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada.
Endometriosis is a chronic disorder in which endometrial-like tissue presents outside the uterus. Patients with endometriosis have been shown to exhibit aberrant immune responses within the lesion microenvironment and in circulation which contribute to the development of endometriosis. Thymic stromal lymphopoietin (TSLP) is an alarmin involved in cell proliferation and the induction of T helper 2 (Th2) inflammation in various diseases, such as asthma, atopic dermatitis, and pancreatic and breast cancer.
View Article and Find Full Text PDFPostoperative Antibiotics After Appendectomy for Acute Appendicitis: No Evidence of Benefit, Even with Intra-Abdominal Fluid.
Ann Surg
March 2025
Sorbonne Université, AP-HP, Department of Digestive Surgery, Hôpital Saint Antoine, Paris, France.
Objective: To evaluate the necessity of postoperative antibiotics following appendectomy for acute appendicitis, particularly in patients with intra-abdominal fluid, and to identify factors associated with postoperative infections.
Background: Postoperative antibiotic use after appendectomy remains controversial, especially in the presence of intra-abdominal fluid. While some surgeons prescribe antibiotics empirically, there is no consensus on whether they reduce the risk of postoperative infections in patients with intra-abdominal fluid accumulation.
Case Report: A modified approach to converting ventriculoperitoneal shunt to ventriculoatrial shunt due to recurrent encapsulation of the peritoneal catheter.
Front Surg
February 2025
Department of Neurosurgery, Chengdu Second People's Hospital, Chengdu, Sichuan, China.
Background: Hydrocephalus is a condition characterized by the accumulation of cerebrospinal fluid (CSF) in the ventricular system due to various causes, including excessive CSF production, impaired circulation, or absorption dysfunction. This condition is often accompanied by ventricular enlargement, compression of brain parenchyma, and increased intracranial pressure. Ventriculoperitoneal (VP) shunting is the first-line treatment for hydrocephalus; however, when the peritoneal catheter becomes obstructed due to encapsulation, the procedure may need to be converted to a ventriculoatrial (VA) shunt, which serves as a second-line treatment.
View Article and Find Full Text PDFA Case Report of Herpes Simplex Virus Associated Peritoneal Dialysis Peritonitis With Novel Use of Intraperitoneal Acyclovir.
Kidney Med
April 2025
Division of Nephrology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.
Viral etiologies, such as herpes simplex virus (HSV), for peritonitis can be misclassified as culture negative peritonitis because of poor accessibility of viral testing in the effluent fluid. Inaccurate diagnosis and subsequent ineffective treatment can lead to unnecessary catheter removal for presumed refractory peritonitis. Here, we report a 73-year-old woman with a history of genital HSV-2 on continuous cyclic peritoneal dialysis who presented with HSV-2 related peritonitis.
View Article and Find Full Text PDFComparative assessment of macrophage responses and antileishmanial efficacy in dynamic vs. Static culture systems utilizing chitosan-based formulations.
PLoS One
March 2025
Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.
The discovery of novel anti-leishmanial compounds is essential due to the limitations of current treatments and the lack of new drugs in development. In this study, we employed the Quasi Vivo 900 medium perfusion system (QV900, Kirkstall Ltd, UK) to simulate physiological fluid flow, allowing us to compare macrophage responses and therapeutic outcomes under dynamic versus static conditions. After 24 hours, phagocytosis and macropinocytosis decreased in all cell types under flow conditions compared to static cultures.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!