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Discovery of new depigmenting compounds and their efficacy to treat hyperpigmentation: Evidence from in vitro study.
J Cosmet Dermatol
June 2019
Department of Bioprocess Technology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Serdang, Malaysia.
Human skin pigmentation is a result of constitutive and facultative pigmentation. Facultative pigmentation is frequently stimulated by UV radiation, pharmacologic drugs, and hormones whereby leads to the development of abnormal skin hyperpigmentation. To date, many state-of-art depigmenting compounds have been studied using in vitro model to treat hyperpigmentation problems for cosmetic dermatological applications; little attention has been made to compare the effectiveness of these depigmenting compounds and their mode of actions.
View Article and Find Full Text PDFTopical manganese peptide in the treatment of photodamaged skin.
J Cosmet Laser Ther
December 2007
Skin Laser & Surgery Specialists of New York & New Jersey, New York, NY, USA.
This study evaluated the effects of a manganese peptide complex in the treatment of various signs of cutaneous facial photodamage. Individuals used a facial serum formulation containing the manganese peptide complex Manganese Tripeptide-1 twice a day for up to 12 weeks. At the end of the treatment period, the individuals and a blinded investigator noted improvement in the appearance of several signs of cutaneous photodamage.
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