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Diploid inbred-based hybrids: fast-forward breeding approach in potatoes.
Physiol Mol Biol Plants
December 2024
ICAR-Central Potato Research Institute, Bemloi, Shimla, Himachal Pradesh 171001 India.
Following the identification of the self-compatibility gene () in diploid potatoes two decades ago, the breeding of inbred based diploid hybrid potatoes made its way. Tetraploid potatoes have a long history of cultivation through domestication and selection. Tetrasomic inheritance, heterozygosity and clonal propagation complicate genetic studies, resulting in a low genetic gain in potato breeding.
View Article and Find Full Text PDFA comprehensive review on genomic insights and advanced technologies for mastitis prevention in dairy animals.
Microb Pathog
December 2024
Livestock Production and Management Section, Indian Veterinary Research Institute, Izatnagar, Bareilly, 243122, UP, India.
Article Synopsis
- Mastitis is a complex disease affecting milk production and reproduction in dairy animals, worsened by breeding practices, climate change, and hygiene issues.
- AI and advanced genomic techniques, such as predictive genomics and CRISPR, have shown promise in identifying genetic traits related to mastitis susceptibility.
- Integration of these technologies supports the development of better diagnostic, preventive, and treatment strategies, offering the potential to enhance dairy herd health and farm profitability.
Runs of homozygosity assessment using reduced representation sequencing highlight the evidence of random mating in emu ().
Genome
December 2024
ICAR- Indian Institute of Agricultural Biotechnology, Ranchi 834010, Jharkhand, India.
The domestication of emu ( began in the 1970s, but their productive characteristics have not undergone significant genetic enhancement. This study investigated the inbreeding and genetic diversity of 50 emus from various farms in Japan using Double digest restriction-site associated DNA sequencing (ddRAD-seq) markers. Single nucleotide polymorphism (SNP) calling revealed 171 975 high-quality SNPs while runs of homozygosity (ROH) analysis identified 1843 homozygous segments, with an average of 36.
View Article and Find Full Text PDFClinical and molecular profile of 20 patients with DOCK8 deficiency-a single-center experience from Southern India.
Immunol Res
December 2024
Paediatric Immunology and Rheumatology Unit, Aster CMI Hospital, Bengaluru, India.
DOCK8 deficiency is the most common cause of autosomal recessive hyper-IgE syndrome (AR-HIES). The clinical spectrum is wide resulting in combined immunodeficiency, atopy, autoimmunity, and malignancies. To study the clinical and molecular profile of 20 patients with DOCK8 deficiency.
View Article and Find Full Text PDFFour Sueus Murayama, 1951 species occur in Southeast Asia and Oceania. They all likely have a female-biased haplodiploid inbreeding mating system and feed on symbiotic ambrosia fungi. These life history traits increase the potential of adventive events.
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