Comparative histological investigation of the gastric pavement epitheliocytes in a number of species (amphibia, reptile, birds, mammals, man including) has demonstrated that in amphibia, protective function of the stomach is connected with the presence of a certain neutral carbohydrate component in its secrete. In reptiles, the barrier function is performed by the neutral carbohydrate component and sialosaccharides, in birds, besides the carbohydrates mentioned, sulphosaccharides, as well. Histochemical properties of the mammal stomach as a barrier are determined by phylogenetically dependent peculiarities of food specialization.
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