A total of 138 aphakic eyes in 109 patients were fitted with lidofilcon B contact lenses for extended wear. These patients were observed for six months to more than three years. Their problems with fit, comfort, infection, lens loss, and visual acuity were reviewed. A comparison between patients in whom the lenses were used successfully and patients in whom the lenses were used unsuccessfully was made, and the causes of failure discussed.
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Graefes Arch Clin Exp Ophthalmol
May 1996
Department of Ophthalmology, Stanford Medical School, CA 94305-5308, USA.
Background: Approximately 85% of Acanthamoeba-contaminated contact lens systems in asymptomatic patients have concurrent bacterial contamination. Pseudomonas aeruginosa and Xanthomonas maltophilia are common contact lens contaminants; we investigated the effect of coincubation of Acanthamoeba adherence to contact lenses.
Methods: A.
Contact lens wear is a predominant risk factor for Acanthamoeba keratitis. The exact nature of the relationship between organism concentration and contact lens adherence is poorly understood. We investigated the effect of Acanthamoeba inoculation concentration on adherence to four categories of contact lenses of varying polymers and water content.
View Article and Find Full Text PDFEye (Lond)
January 1994
Public Health Laboratory, Royal United Hospital, UK.
Trophozoite and cyst adherence of two Acanthamoeba keratitis strains (PHL/530 and PHL/978) to four types of unworn soft contact lens and their removal by cleaning agents were studied. Greater adherence of the trophozoites compared with the cysts was recorded for both strains. Trophozoites of PHL/530 adhered in greater numbers to type I lenses (61.
View Article and Find Full Text PDFOptom Vis Sci
November 1991
Allergan Optical, Irvine, California.
An artificial tear solution containing the major types of proteins, glycoproteins, and lipids represented in human tears has been developed. The adsorption of lipids onto various hydrogel lens materials (polymacon, lidofilcon A, phemfilcon A, etafilcon A) was examined by exposing the lenses to our artificial tear solution for 18 h. The adsorbed lipids were detected using Nile red stain.
View Article and Find Full Text PDFInvest Ophthalmol Vis Sci
March 1991
Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts.
The authors determined the attachment of a single strain of Pseudomonas aeruginosa to seven brands of hydrogel soft contact lenses (SCLs): nonionic, low-water (polymacon and crofilcon); nonionic, high-water (lidofilcon); ionic, high-water (bufilcon, etafilcon, and perfilcon); and surface-neutralized, high-water (bufilcon). The lenses were exposed to a 1 X 10(8) colony-forming units (CFU)/ml P. aeruginosa suspension either when new and sterile or after 24 hr of continuous wear in rabbit eyes.
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