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microRNA as an Important Mediator in the Regulation of Male Reproduction: Current State of the Problem.
Int J Mol Sci
December 2024
Russian Research Institute of Farm Animal Genetics and Breeding-Branch of the L.K. Ernst Federal Research Center for Animal Husbandry, Pushkin, Saint-Petersburg 196625, Russia.
During all periods of male ontogenesis, physiological processes responsible for the correct functioning of reproductive organs and spermatogenesis are under the influence of various factors (neuro-humoral, genetic, and paratypical). Recently, the attention of researchers has increasingly turned to the study of epigenetic factors. In scientific publications, one can increasingly find references to the direct role of microRNAs, small non-coding RNAs involved in post-transcriptional regulation of gene expression, in the processes of development and functioning of reproductive organs.
View Article and Find Full Text PDFThe Role of Activated Stromal Cells in Fibrotic Foci Formation and Reversion.
Cells
December 2024
Centre for Regenerative Medicine, Medical Research and Educational Institute, Lomonosov Moscow State University, 119192 Moscow, Russia.
Fibrotic focus is a pivotal morphofunctional unit in developing fibrosis in various tissues. For most fibrotic diseases, including progressive forms, the foci are considered unable to remodel and contribute to the worsening of prognosis. Unfortunately, the dynamics of the fibrotic focus formation and resolution remains understudied.
View Article and Find Full Text PDF[Characteristics of postmortem changes in the brain].
Sud Med Ekspert
December 2024
National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov, Moscow, Russia.
The study aimed to analyze the literature data on postmortem changes in the brain and their use to determine the time since death. The earliest manifestations of brain cell autolysis are detected by electron microscopy (15-20 minutes after death). The longer the postmortem period, the more morphofunctional changes in the brain are revealed by histological, histochemical, and immunohistochemical studies.
View Article and Find Full Text PDFHindlimb biomechanics of Lagosuchus talampayensis (Archosauria, Dinosauriformes), with comments on skeletal morphology.
J Anat
December 2024
Structure and Motion Laboratory, Department of Comparative Biomedical Sciences, Royal Veterinary College, North Mymms, Hatfield, UK.
Lagosuchus talampayensis is a small-bodied (~0.5 m long) Late Triassic dinosauriform archosaur from Argentina. Lagosuchus long has been a pivotal taxon for reconstructing the evolution of form and function on the dinosaur lineage.
View Article and Find Full Text PDFIncreased metabolic demand reveals morpho-functional impacts caused by settleable atmospheric particulate matter on fish gills.
Environ Toxicol Pharmacol
December 2024
Department of Physiological Sciences, Federal University of São Carlos, São Carlos, SP, Brazil.
Exposure to environmentally relevant levels of settleable atmospheric particulate matter (SePM) limits the aerobic performance of inactive healthy adult fish. We evaluated the gill morpho-functional impacts (gill structure and ionic balance) caused by SePM exposure (96 h) in Nile tilapia when fish is impelled to maximal aerobic swimming effort. In control fish, swimming reduced epithelial filament thickness (EFT, 25 %), increased the distance between lamellae (DL, 21 %), and reduced the plasma Na (5 %).
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